Caffeine release and absorption from caffeinated gums

Cecile Morris; Sophie M.  Viriot; Qurat U.A.  Farooq Mirza; Gordon Morris; Anthony  Lynn

doi:10.1039/C9FO00431A

Caffeine release and absorption from caffeinated gums

Cecile Morris, Sophie M. Viriot, Qurat U.A. Farooq Mirza, Gordon Morris, Anthony Lynn

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

The objectives of this study were to estimate the impact of chewing time on caffeine release from gum and to understand caffeine pharmacokinetics. Caffeine release increased with chewing time (2 min < 5 min < 10 min). Furthermore, two plasma caffeine concentration peaks were observed suggesting that caffeine absorption occurs both through the oral mucosa and gastrointestinal tract. This is of practical relevance to maximise caffeine doses and to synchronise effort with peak caffeine concentration.

Original language	English
Pages (from-to)	1792-1796
Number of pages	5
Journal	Food and Function
Volume	10
Issue number	4
Early online date	22 Mar 2019
DOIs	https://doi.org/10.1039/C9FO00431A
Publication status	Published - 1 Apr 2019

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10.1039/C9FO00431ALicence: Unspecified

Release and absorption of caffeine from gumsAccepted author manuscript, 3.23 MBLicence: Unspecified

Cite this

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AU - Lynn, Anthony

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AB - The objectives of this study were to estimate the impact of chewing time on caffeine release from gum and to understand caffeine pharmacokinetics. Caffeine release increased with chewing time (2 min < 5 min < 10 min). Furthermore, two plasma caffeine concentration peaks were observed suggesting that caffeine absorption occurs both through the oral mucosa and gastrointestinal tract. This is of practical relevance to maximise caffeine doses and to synchronise effort with peak caffeine concentration.

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Caffeine release and absorption from caffeinated gums

Abstract

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