Caffeine release and absorption from caffeinated gums

Cecile Morris, Sophie M. Viriot, Qurat U.A. Farooq Mirza, Gordon Morris, Anthony Lynn

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

The objectives of this study were to estimate the impact of chewing time on caffeine release from gum and to understand caffeine pharmacokinetics. Caffeine release increased with chewing time (2 min < 5 min < 10 min). Furthermore, two plasma caffeine concentration peaks were observed suggesting that caffeine absorption occurs both through the oral mucosa and gastrointestinal tract. This is of practical relevance to maximise caffeine doses and to synchronise effort with peak caffeine concentration.
Original languageEnglish
Pages (from-to)1792-1796
Number of pages5
JournalFood and Function
Volume10
Issue number4
Early online date22 Mar 2019
DOIs
Publication statusPublished - 1 Apr 2019

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