Catalytic mechanisms and specificities of glutathione peroxidases: Variations of a basic scheme

Keyphrases

• Catalytic Mechanism 100%
• Redox Center 100%
• Catalytic Specificity 100%
• Glutathione Peroxidase (GSH-Px) 100%
• Vertebrates 66%
• Selenocysteine 66%
• Glutathione Peroxidase 4 (GPX4) 66%
• Cysteine 66%
• Metabolism 33%
• Order of Magnitude 33%
• Induced Apoptosis 33%
• Transcription Factor 33%
• Molecular Mechanism 33%
• Disulfide 33%
• Structural Features 33%
• Binding Residues 33%
• Redox-active 33%
• Thiolate 33%
• Protein Thiols 33%
• Lipid Hydroperoxides 33%
• Redoxin 33%
• Asparagine 33%
• Regulation of Inflammatory Response 33%
• 12/15-Lipoxygenase 33%
• Common Denominator 33%
• Selenolate 33%
• Selenylation 33%
• GPX1 33%
• Hydroperoxides 33%
• Hydrogen Peroxide 33%
• Tryptophan 33%
• Glutamine 33%
• Redox Sensing 33%
• Kinetic Mechanism 33%
• Heterodimer Formation 33%
• Architectural Context 33%

Biochemistry, Genetics and Molecular Biology

• Enzyme 100%
• Catalytic Mechanism 100%
• Glutathione Peroxidase 100%
• Selenocysteine 100%
• Cysteine 100%
• Programmed Cell Death 50%
• Metabolic Pathway 50%
• Transcription Factor 50%
• Disulfide 50%
• Glutamine 50%
• Thiol 50%
• Thiolates 50%
• Lipoxygenase 50%
• Lipid 50%
• Tryptophan 50%
• Hydrogen Peroxide 50%
• Asparagine 50%