Central nervous system depressant effect of Hoslundia opposita Vahl

O. A. Olajide; S. O. Awe; J. M. Makinde

doi:10.1002/(SICI)1099-1573(199908/09)13:5<425::AID-PTR466>3.0.CO;2-1

Central nervous system depressant effect of Hoslundia opposita Vahl

O. A. Olajide, S. O. Awe, J. M. Makinde

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

The chloroform extract of the dried root of Hoslundia opposita has been evaluated for effects on the central nervous system (CNS). The extract significantly potentiated the phenobarbitone sleeping time in mice and produced a 60% protection against leptazol-induced convulsion. Neuropharmacological screening revealed CNS depression.

Original language	English
Pages (from-to)	425-426
Number of pages	2
Journal	Phytotherapy Research
Volume	13
Issue number	5
DOIs	https://doi.org/10.1002/(SICI)1099-1573(199908/09)13:5<425::AID-PTR466>3.0.CO;2-1
Publication status	Published - 18 Aug 1999
Externally published	Yes

Access to Document

10.1002/(SICI)1099-1573(199908/09)13:5<425::AID-PTR466>3.0.CO;2-1

Cite this

@article{76b867bf013a40e6b934d7ca4484e530,

title = "Central nervous system depressant effect of Hoslundia opposita Vahl",

abstract = "The chloroform extract of the dried root of Hoslundia opposita has been evaluated for effects on the central nervous system (CNS). The extract significantly potentiated the phenobarbitone sleeping time in mice and produced a 60% protection against leptazol-induced convulsion. Neuropharmacological screening revealed CNS depression.",

keywords = "Anticonvulsant, CNS depression, Hoslundia opposita Vahl",

author = "Olajide, {O. A.} and Awe, {S. O.} and Makinde, {J. M.}",

year = "1999",

month = aug,

day = "18",

doi = "10.1002/(SICI)1099-1573(199908/09)13:5<425::AID-PTR466>3.0.CO;2-1",

language = "English",

volume = "13",

pages = "425--426",

journal = "Phytotherapy Research",

issn = "0951-418X",

publisher = "John Wiley and Sons Ltd",

number = "5",

}

TY - JOUR

T1 - Central nervous system depressant effect of Hoslundia opposita Vahl

AU - Olajide, O. A.

AU - Awe, S. O.

AU - Makinde, J. M.

PY - 1999/8/18

Y1 - 1999/8/18

N2 - The chloroform extract of the dried root of Hoslundia opposita has been evaluated for effects on the central nervous system (CNS). The extract significantly potentiated the phenobarbitone sleeping time in mice and produced a 60% protection against leptazol-induced convulsion. Neuropharmacological screening revealed CNS depression.

AB - The chloroform extract of the dried root of Hoslundia opposita has been evaluated for effects on the central nervous system (CNS). The extract significantly potentiated the phenobarbitone sleeping time in mice and produced a 60% protection against leptazol-induced convulsion. Neuropharmacological screening revealed CNS depression.

KW - Anticonvulsant

KW - CNS depression

KW - Hoslundia opposita Vahl

UR - http://www.scopus.com/inward/record.url?scp=0032770952&partnerID=8YFLogxK

U2 - 10.1002/(SICI)1099-1573(199908/09)13:5<425::AID-PTR466>3.0.CO;2-1

DO - 10.1002/(SICI)1099-1573(199908/09)13:5<425::AID-PTR466>3.0.CO;2-1

M3 - Article

C2 - 10441785

AN - SCOPUS:0032770952

VL - 13

SP - 425

EP - 426

JO - Phytotherapy Research

JF - Phytotherapy Research

SN - 0951-418X

IS - 5

ER -

Central nervous system depressant effect of Hoslundia opposita Vahl

Abstract

Access to Document

Other files and links

Fingerprint

Cite this