Central nervous system depressant effect of Hoslundia opposita Vahl

O. A. Olajide, S. O. Awe, J. M. Makinde

Research output: Contribution to journalArticle

7 Citations (Scopus)


The chloroform extract of the dried root of Hoslundia opposita has been evaluated for effects on the central nervous system (CNS). The extract significantly potentiated the phenobarbitone sleeping time in mice and produced a 60% protection against leptazol-induced convulsion. Neuropharmacological screening revealed CNS depression.

Original languageEnglish
Pages (from-to)425-426
Number of pages2
JournalPhytotherapy Research
Issue number5
Publication statusPublished - 18 Aug 1999
Externally publishedYes


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