Chemoenzymatic dynamic kinetic resolution of secondary amines

Matthew Stirling, John Blacker, Michael I. Page

Research output: Contribution to journalArticle

103 Citations (Scopus)

Abstract

The kinetic resolution of amines using a novel iridium based catalyst coupled with an enzyme catalysed step is achieved on a large scale with high yields and ee.

LanguageEnglish
Pages1247-1250
Number of pages4
JournalTetrahedron Letters
Volume48
Issue number7
DOIs
Publication statusPublished - 12 Feb 2007

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Iridium
Amines
Catalysts
Kinetics
Enzymes

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Stirling, Matthew ; Blacker, John ; Page, Michael I. / Chemoenzymatic dynamic kinetic resolution of secondary amines. In: Tetrahedron Letters. 2007 ; Vol. 48, No. 7. pp. 1247-1250.
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Chemoenzymatic dynamic kinetic resolution of secondary amines. / Stirling, Matthew; Blacker, John; Page, Michael I.

In: Tetrahedron Letters, Vol. 48, No. 7, 12.02.2007, p. 1247-1250.

Research output: Contribution to journalArticle

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