Chemoenzymatic dynamic kinetic resolution of secondary amines

Matthew Stirling; John Blacker; Michael I. Page

doi:10.1016/j.tetlet.2006.12.032

Chemoenzymatic dynamic kinetic resolution of secondary amines

Matthew Stirling, John Blacker, Michael I. Page

School of Applied Sciences

Research output: Contribution to journal › Article › peer-review

120 Citations (Scopus)

Abstract

The kinetic resolution of amines using a novel iridium based catalyst coupled with an enzyme catalysed step is achieved on a large scale with high yields and ee.

Original language	English
Pages (from-to)	1247-1250
Number of pages	4
Journal	Tetrahedron Letters
Volume	48
Issue number	7
DOIs	https://doi.org/10.1016/j.tetlet.2006.12.032
Publication status	Published - 12 Feb 2007

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title = "Chemoenzymatic dynamic kinetic resolution of secondary amines",

abstract = "The kinetic resolution of amines using a novel iridium based catalyst coupled with an enzyme catalysed step is achieved on a large scale with high yields and ee.",

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AU - Blacker, John

AU - Page, Michael I.

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N2 - The kinetic resolution of amines using a novel iridium based catalyst coupled with an enzyme catalysed step is achieved on a large scale with high yields and ee.

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JO - Tetrahedron Letters

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Chemoenzymatic dynamic kinetic resolution of secondary amines

Abstract

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