Chemoenzymatic dynamic kinetic resolution of secondary amines

Matthew Stirling; John Blacker; Michael I. Page

doi:10.1016/j.tetlet.2006.12.032

Chemoenzymatic dynamic kinetic resolution of secondary amines

Matthew Stirling, John Blacker, Michael I. Page

School of Applied Sciences

NPILPharma

Research output: Contribution to journal › Article › peer-review

120 Citations (Scopus)

Abstract

The kinetic resolution of amines using a novel iridium based catalyst coupled with an enzyme catalysed step is achieved on a large scale with high yields and ee.

Original language	English
Pages (from-to)	1247-1250
Number of pages	4
Journal	Tetrahedron Letters
Volume	48
Issue number	7
DOIs	https://doi.org/10.1016/j.tetlet.2006.12.032
Publication status	Published - 12 Feb 2007

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title = "Chemoenzymatic dynamic kinetic resolution of secondary amines",

abstract = "The kinetic resolution of amines using a novel iridium based catalyst coupled with an enzyme catalysed step is achieved on a large scale with high yields and ee.",

author = "Matthew Stirling and John Blacker and Page, \{Michael I.\}",

year = "2007",

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doi = "10.1016/j.tetlet.2006.12.032",

language = "English",

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journal = "Tetrahedron Letters",

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T1 - Chemoenzymatic dynamic kinetic resolution of secondary amines

AU - Stirling, Matthew

AU - Blacker, John

AU - Page, Michael I.

PY - 2007/2/12

Y1 - 2007/2/12

N2 - The kinetic resolution of amines using a novel iridium based catalyst coupled with an enzyme catalysed step is achieved on a large scale with high yields and ee.

AB - The kinetic resolution of amines using a novel iridium based catalyst coupled with an enzyme catalysed step is achieved on a large scale with high yields and ee.

UR - https://www.scopus.com/pages/publications/33846184753

U2 - 10.1016/j.tetlet.2006.12.032

DO - 10.1016/j.tetlet.2006.12.032

M3 - Article

AN - SCOPUS:33846184753

SN - 0040-4039

VL - 48

SP - 1247

EP - 1250

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 7

ER -

Chemoenzymatic dynamic kinetic resolution of secondary amines

Abstract

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