Chiral Aryl Iodide-Catalyzed Enantioselective α-Oxidation of Ketones

Arantxa Rodríguez, Wesley J. Moran

Research output: Contribution to journalArticlepeer-review

57 Citations (Scopus)


Several chiral aryl iodides were synthesized and assessed as catalysts in the enantioselective α-oxytosylation of propiophenone and the oxidative cyclization of 5-oxo-5-phenylpentanoic acid to 5-benzoyldihydrofuran-2(3H)-one. The highest enantioselectivities obtained were 18 and 51% ee, respectively. The latter is the highest selectivity recorded to date for this reaction.

Original languageEnglish
Pages (from-to)1178-1182
Number of pages5
Issue number8
Publication statusPublished - Apr 2012


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