Cohen syndrome-associated protein COH1 physically and functionally interacts with the small GTPase RAB6 at the Golgi complex and directs neurite outgrowth

Keyphrases

• Small GTPase 100%
• Golgi Complex 100%
• Cohen Syndrome 100%
• Neurite Outgrowth 100%
• COH1 100%
• Rab6 100%
• Associated Proteins 100%
• Co-immunoprecipitation (co-IP) 10%
• Autosomal Recessive 10%
• Intellectual Disability 10%
• Physical Interaction 10%
• Scaffold Protein 10%
• Effector Proteins 10%
• Primary Neurons 10%
• Membrane Preparation 10%
• SiRNA Knockdown 10%
• Postnatal Microcephaly 10%
• VPS13B 10%
• Structural Function 10%
• Major Features 10%
• Structural Repair 10%
• Lipid Membrane 10%
• Axonal Outgrowth 10%
• Brain Size 10%
• Causal Link 10%
• Neuritogenesis 10%
• Retinal Dystrophy 10%
• Constitutively Active 10%

Neuroscience

• Neurite Outgrowth 100%
• GTPase 100%
• Neuritogenesis 50%
• Membrane Lipid 50%
• Scaffold Protein 50%
• Retinal Dystrophy 50%
• Microcephaly 50%
• Lipid Membrane 50%

Biochemistry, Genetics and Molecular Biology

• Small GTPase 100%
• Golgi Apparatus 100%
• Neurite Outgrowth 100%
• RNA Interference 16%
• Autosomal Recessive Inheritance 16%
• Membrane Lipid 16%
• Intellectual Disability 16%
• Brain Size 16%
• Solubilization 16%
• Scaffold Protein 16%