TY - JOUR
T1 - Conical scan polarization-sensitive optical coherence tomography
AU - Lu, Zenghai
AU - Kasaragod, Deepa
AU - Matcher, Stephen J.
PY - 2014/3/1
Y1 - 2014/3/1
N2 - We report on a new articular cartilage imaging technique with potential for clinical arthroscopic use, by supplementing the variableincidence- angle polarization-sensitive optical coherence tomography method previously developed by us with a conical beam scan protocol. The technique is validated on bovine tendon by comparing experimental data with simulated data generated using the extended Jones matrix calculus. A unique capability of this new optical technique is that it can locate the "brushing direction" of collagen fibers in articular cartilage, which is structural information that extends beyond established methods such as split-line photography or birefringent fast-axis measurement in that it is uniquely defined over the full azimuthal-angle range of (-π, + π). The mapping of this direction over the cartilage surface may offer insights into the optimal design of tissue-engineering scaffolds for cartilage repair.
AB - We report on a new articular cartilage imaging technique with potential for clinical arthroscopic use, by supplementing the variableincidence- angle polarization-sensitive optical coherence tomography method previously developed by us with a conical beam scan protocol. The technique is validated on bovine tendon by comparing experimental data with simulated data generated using the extended Jones matrix calculus. A unique capability of this new optical technique is that it can locate the "brushing direction" of collagen fibers in articular cartilage, which is structural information that extends beyond established methods such as split-line photography or birefringent fast-axis measurement in that it is uniquely defined over the full azimuthal-angle range of (-π, + π). The mapping of this direction over the cartilage surface may offer insights into the optimal design of tissue-engineering scaffolds for cartilage repair.
KW - Clinical arthroscopic
KW - Polarization-sensitive optical coherence tomography (PS-OCT)
KW - Jones matrix calculus
UR - http://www.scopus.com/inward/record.url?scp=84895765832&partnerID=8YFLogxK
U2 - 10.1364/BOE.5.000752
DO - 10.1364/BOE.5.000752
M3 - Article
AN - SCOPUS:84895765832
VL - 5
SP - 752
EP - 762
JO - Biomedical Optics Express
JF - Biomedical Optics Express
SN - 2156-7085
IS - 3
ER -