Conical scan polarization-sensitive optical coherence tomography

Zenghai Lu, Deepa Kasaragod, Stephen J. Matcher

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)


We report on a new articular cartilage imaging technique with potential for clinical arthroscopic use, by supplementing the variableincidence- angle polarization-sensitive optical coherence tomography method previously developed by us with a conical beam scan protocol. The technique is validated on bovine tendon by comparing experimental data with simulated data generated using the extended Jones matrix calculus. A unique capability of this new optical technique is that it can locate the "brushing direction" of collagen fibers in articular cartilage, which is structural information that extends beyond established methods such as split-line photography or birefringent fast-axis measurement in that it is uniquely defined over the full azimuthal-angle range of (-π, + π). The mapping of this direction over the cartilage surface may offer insights into the optimal design of tissue-engineering scaffolds for cartilage repair.

Original languageEnglish
Pages (from-to)752-762
Number of pages11
JournalBiomedical Optics Express
Issue number3
Early online date18 Feb 2014
Publication statusPublished - 1 Mar 2014
Externally publishedYes


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