Conjugate additions of lithium dialkynylcuprates [(RC≡C)2CuLi] to activated chromones. Unexpected formation of the 6H-bis[1]benzopyrano[2,3-b:3′,4′-e]pyridine system

Dan E. Daia, Christopher D. Gabbutt, B. Mark Heron, John D. Hepworth, Michael B. Hursthouse, K. M.Abdul Malik

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Lithium dialkynylcuprates [(RC≡C)2CuLi], 1a-d, are easily generated and undergo conjugate additions to activated chromones giving 2-alkynylchroman-4-ones 4a-d, 13, 15c,d and 5, however, 1,4-additions to 3 proceed anomalously to give the eneynonitriles 6a-b and the bisbenzopyranopyridine 7.

Original languageEnglish
Pages (from-to)1461-1464
Number of pages4
JournalTetrahedron Letters
Volume44
Issue number7
Early online date30 Jan 2003
DOIs
Publication statusPublished - 10 Feb 2003
Externally publishedYes

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