Construction of β-Haloenamides via Direct Copper-Promoted Coupling of Lactams with 2-Chloro and 2-Bromo Vinyliodides

Cuixiang Sun; Jason E. Camp; Steven M. Weinreb

doi:10.1021/ol060093a

Construction of β-Haloenamides via Direct Copper-Promoted Coupling of Lactams with 2-Chloro and 2-Bromo Vinyliodides

Cuixiang Sun, Jason E. Camp, Steven M. Weinreb

Research output: Contribution to journal › Article › peer-review

61 Citations (Scopus)

Abstract

Cu(I)-catalyzed coupling of lactams with (E)-2-chlorovinyliodides or (E)-2-bromovinyliodides produces the corresponding β-haloenamides in moderate to excellent yields.

Original language	English
Pages (from-to)	1779-1781
Number of pages	3
Journal	Organic Letters
Volume	8
Issue number	9
DOIs	https://doi.org/10.1021/ol060093a
Publication status	Published - 27 Apr 2006
Externally published	Yes

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@article{69e9af695b264b3bb6362beffb8b2d56,

title = "Construction of β-Haloenamides via Direct Copper-Promoted Coupling of Lactams with 2-Chloro and 2-Bromo Vinyliodides",

abstract = "Cu(I)-catalyzed coupling of lactams with (E)-2-chlorovinyliodides or (E)-2-bromovinyliodides produces the corresponding β-haloenamides in moderate to excellent yields.",

author = "Cuixiang Sun and Camp, {Jason E.} and Weinreb, {Steven M.}",

year = "2006",

month = apr,

day = "27",

doi = "10.1021/ol060093a",

language = "English",

volume = "8",

pages = "1779--1781",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "9",

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TY - JOUR

T1 - Construction of β-Haloenamides via Direct Copper-Promoted Coupling of Lactams with 2-Chloro and 2-Bromo Vinyliodides

AU - Sun, Cuixiang

AU - Camp, Jason E.

AU - Weinreb, Steven M.

PY - 2006/4/27

Y1 - 2006/4/27

N2 - Cu(I)-catalyzed coupling of lactams with (E)-2-chlorovinyliodides or (E)-2-bromovinyliodides produces the corresponding β-haloenamides in moderate to excellent yields.

AB - Cu(I)-catalyzed coupling of lactams with (E)-2-chlorovinyliodides or (E)-2-bromovinyliodides produces the corresponding β-haloenamides in moderate to excellent yields.

UR - http://www.scopus.com/inward/record.url?scp=33646459483&partnerID=8YFLogxK

UR - http://pubs.acs.org/journal/orlef7

U2 - 10.1021/ol060093a

DO - 10.1021/ol060093a

M3 - Article

C2 - 16623549

AN - SCOPUS:33646459483

SN - 1523-7060

VL - 8

SP - 1779

EP - 1781

JO - Organic Letters

JF - Organic Letters

IS - 9

ER -

Construction of β-Haloenamides via Direct Copper-Promoted Coupling of Lactams with 2-Chloro and 2-Bromo Vinyliodides

Abstract

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