Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD

Graeme Hewitt, Valerie Borel, Sandra Segura-Bayona, Tohru Takaki, Phil Ruis, Roberto Bellelli, Laura Lehmann, Lucia Sommerova, Aleksandra Vancevska, Antonia Tomas-Loba, Kang Zhu, Christopher Cooper, Kasper Fugger, Harshil Patel, Robert Goldstone, Deborah Schneider-Luftman,, Ellie Herbert, Gordon Stamp, Rachel Brough, Stephen PettittChristopher Lord, Stephen West, Ivan Ahel, Dragana Ahel, Ross Chapman, Sebastian Deindl, Simon Boulton

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Medicine & Life Sciences