Design and synthesis of chiral urea-derived iodoarenes and their assessment in the enantioselective dearomatizing cyclization of a naphthyl amide

Muhammad Tariq, Wesley J. Moran

Research output: Contribution to journalArticle

Abstract

A novel family of urea-derived chiral iodoarenes was designed and synthesized for use in enantioselective iodine(I/III) catalysis. Their preparation required the development of a bidirectional synthetic strategy. These new chiral iodoarenes were assessed as catalysts in the dearomatizing cyclization of a naphthyl amide and provided moderate yields of product in some cases with low enantioselectivities.
Original languageEnglish
Article number131634
JournalTetrahedron
Early online date3 Oct 2020
DOIs
Publication statusE-pub ahead of print - 3 Oct 2020

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