Determination of the collagen fiber 'Brushing direction' in articular cartilage by conical-scan polarization-sensitive optical coherence tomography

Zenghai Lu; Deepa Kasaragod; Stephen J. Matcher

doi:10.1117/12.2036731

Determination of the collagen fiber 'Brushing direction' in articular cartilage by conical-scan polarization-sensitive optical coherence tomography

Zenghai Lu, Deepa Kasaragod, Stephen J. Matcher

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

A new imaging technique is presented by introducing the concept of conical scan to the variable-incidenc-angle polarimetry (VIA) previously developed by our group. The technique would facilitate the translating of the VIA technique to the clinic by simplifying the requirements of measurements in two orthogonal planes by using a conical scan protocol. Conical scan PS-OCT images could illustrate directly the azimuthal angle of the collage fibers in birefringent tissue, which was validated by measurements on a bovine tendon. We have showed the unique technique can be used to locate the "brushing direction" of collagen fibers in articular cartilage. Measuring this direction over the cartilage surface could potentially help designing of tissue-engineering scaffolds for cartilage repair.

Original language	English
Title of host publication	Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII
Editors	Josephe A. Izatt, James G. Fujimoto, Valery V. Tuchin
Publisher	SPIE
Number of pages	6
Volume	8934
ISBN (Print)	9780819498472
DOIs	https://doi.org/10.1117/12.2036731
Publication status	Published - 4 Mar 2014
Externally published	Yes
Event	Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII - San Francisco, United States Duration: 1 Feb 2014 → 6 Feb 2014 Conference number: 18

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	8934
ISSN (Print)	1605-7422

Conference

Conference	Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII
Country/Territory	United States
City	San Francisco
Period	1/02/14 → 6/02/14

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Lu, Z., Kasaragod, D., & Matcher, S. J. (2014). Determination of the collagen fiber 'Brushing direction' in articular cartilage by conical-scan polarization-sensitive optical coherence tomography. In J. A. Izatt, J. G. Fujimoto, & V. V. Tuchin (Eds.), Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII (Vol. 8934). [89341Q] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8934). SPIE. https://doi.org/10.1117/12.2036731

Lu, Zenghai ; Kasaragod, Deepa ; Matcher, Stephen J. / Determination of the collagen fiber 'Brushing direction' in articular cartilage by conical-scan polarization-sensitive optical coherence tomography. Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII. editor / Josephe A. Izatt ; James G. Fujimoto ; Valery V. Tuchin. Vol. 8934 SPIE, 2014. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).

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title = "Determination of the collagen fiber 'Brushing direction' in articular cartilage by conical-scan polarization-sensitive optical coherence tomography",

abstract = "A new imaging technique is presented by introducing the concept of conical scan to the variable-incidenc-angle polarimetry (VIA) previously developed by our group. The technique would facilitate the translating of the VIA technique to the clinic by simplifying the requirements of measurements in two orthogonal planes by using a conical scan protocol. Conical scan PS-OCT images could illustrate directly the azimuthal angle of the collage fibers in birefringent tissue, which was validated by measurements on a bovine tendon. We have showed the unique technique can be used to locate the {"}brushing direction{"} of collagen fibers in articular cartilage. Measuring this direction over the cartilage surface could potentially help designing of tissue-engineering scaffolds for cartilage repair.",

keywords = "Brushing direction, Polarization-sensitive OCT, Cartilage, Collagen, Tissues, Optical coherence tomography, Imaging systems, Natural surfaces, 3D image processing, Birefringence, Polarimetry, Structured optical fibers",

author = "Zenghai Lu and Deepa Kasaragod and Matcher, {Stephen J.}",

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doi = "10.1117/12.2036731",

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Lu, Z, Kasaragod, D & Matcher, SJ 2014, Determination of the collagen fiber 'Brushing direction' in articular cartilage by conical-scan polarization-sensitive optical coherence tomography. in JA Izatt, JG Fujimoto & VV Tuchin (eds), Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII. vol. 8934, 89341Q, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 8934, SPIE, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII, San Francisco, California, United States, 1/02/14. https://doi.org/10.1117/12.2036731

Determination of the collagen fiber 'Brushing direction' in articular cartilage by conical-scan polarization-sensitive optical coherence tomography. / Lu, Zenghai; Kasaragod, Deepa; Matcher, Stephen J.

Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII. ed. / Josephe A. Izatt; James G. Fujimoto; Valery V. Tuchin. Vol. 8934 SPIE, 2014. 89341Q (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8934).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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PY - 2014/3/4

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N2 - A new imaging technique is presented by introducing the concept of conical scan to the variable-incidenc-angle polarimetry (VIA) previously developed by our group. The technique would facilitate the translating of the VIA technique to the clinic by simplifying the requirements of measurements in two orthogonal planes by using a conical scan protocol. Conical scan PS-OCT images could illustrate directly the azimuthal angle of the collage fibers in birefringent tissue, which was validated by measurements on a bovine tendon. We have showed the unique technique can be used to locate the "brushing direction" of collagen fibers in articular cartilage. Measuring this direction over the cartilage surface could potentially help designing of tissue-engineering scaffolds for cartilage repair.

AB - A new imaging technique is presented by introducing the concept of conical scan to the variable-incidenc-angle polarimetry (VIA) previously developed by our group. The technique would facilitate the translating of the VIA technique to the clinic by simplifying the requirements of measurements in two orthogonal planes by using a conical scan protocol. Conical scan PS-OCT images could illustrate directly the azimuthal angle of the collage fibers in birefringent tissue, which was validated by measurements on a bovine tendon. We have showed the unique technique can be used to locate the "brushing direction" of collagen fibers in articular cartilage. Measuring this direction over the cartilage surface could potentially help designing of tissue-engineering scaffolds for cartilage repair.

KW - Brushing direction

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KW - Tissues

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KW - 3D image processing

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BT - Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII

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PB - SPIE

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ER -

Lu Z, Kasaragod D, Matcher SJ. Determination of the collagen fiber 'Brushing direction' in articular cartilage by conical-scan polarization-sensitive optical coherence tomography. In Izatt JA, Fujimoto JG, Tuchin VV, editors, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVIII. Vol. 8934. SPIE. 2014. 89341Q. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.2036731

Determination of the collagen fiber 'Brushing direction' in articular cartilage by conical-scan polarization-sensitive optical coherence tomography

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