Novel electron-deficient chiral hypervalent iodine reagents were prepared in good overall yields. The reactivity and stereoselectivity of these reagents in oxidative rearrangements of alkenes to α-aryl ketones were investigated. The results show that the new reagents have good reactivity and generate products with high enantiomeric excess.
Qurban, J., Elsherbini, M., & Wirth, T. (2017). Electron-Deficient Chiral Lactic Acid-Based Hypervalent Iodine Reagents. Journal of Organic Chemistry, 82(22), 11872-11876. https://doi.org/10.1021/acs.joc.7b01571