Abstract
The pharmacological properties of nutmeg oil in animal models were investigated. The oil exhibited an anti-inflammatory effect on acute inflammation. An analgesic effect was produced by the oil in the acetic acid-induced writhing model and in the late phase of the formalin-induced licking. The oil showed an antipyretic activity, and antithrombotic and anti-diarrhoeal properties. Sub-acute administration of the oil produced gastric ulcerations. These data indicate that nutmeg oil showed pharmacological activities similar to those of non-steroidal anti-inflammatory drugs, in addition to anti-diarrhoeal activity.
| Original language | English |
|---|---|
| Pages (from-to) | 385-390 |
| Number of pages | 6 |
| Journal | Pharmaceutical Biology |
| Volume | 38 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 1 Dec 2000 |
| Externally published | Yes |