Evidence for biogeographic patterning of mitochondrial DNA sequences in Eastern horse populations

A. McGahern, M. A.M. Bower, C. J. Edwards, P. O. Brophy, G. Sulimova, I. Zakharov, M. Vizuete-Forster, M. Levine, S. Li, D. E. MacHugh, E. W. Hill

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Abstract

Equine mitochondrial DNA (mtDNA) phylogeny reconstruction reveals a complex pattern of variation unlike that seen in other large domesticates. It is likely that this pattern reflects a process of multiple and repeated, although not necessarily independent, domestication events. Until now, no clear geographic affiliation of clades has been apparent. In this study, amova analyses have revealed a significant non-random distribution of the diversity among equine populations when seven newly sequenced Eurasian populations were examined in the context of previously published sequences. The association of Eastern mtDNA types in haplogroup F was highly significant using Fisher's exact test of independence (P = 0.00000). For the first time, clear biogeographic partitioning has been detected in equine mtDNA sequence.

Original languageEnglish
Pages (from-to)494-497
Number of pages4
JournalAnimal Genetics
Volume37
Issue number5
Early online date1 Sep 2006
DOIs
Publication statusPublished - 1 Oct 2006
Externally publishedYes

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Mitochondrial DNA
Horses
mitochondrial DNA
horses
nucleotide sequences
Population
Phylogeny
domestication
phylogeny
testing

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McGahern, A., Bower, M. A. M., Edwards, C. J., Brophy, P. O., Sulimova, G., Zakharov, I., ... Hill, E. W. (2006). Evidence for biogeographic patterning of mitochondrial DNA sequences in Eastern horse populations. Animal Genetics, 37(5), 494-497. https://doi.org/10.1111/j.1365-2052.2006.01495.x
McGahern, A. ; Bower, M. A.M. ; Edwards, C. J. ; Brophy, P. O. ; Sulimova, G. ; Zakharov, I. ; Vizuete-Forster, M. ; Levine, M. ; Li, S. ; MacHugh, D. E. ; Hill, E. W. / Evidence for biogeographic patterning of mitochondrial DNA sequences in Eastern horse populations. In: Animal Genetics. 2006 ; Vol. 37, No. 5. pp. 494-497.
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McGahern, A, Bower, MAM, Edwards, CJ, Brophy, PO, Sulimova, G, Zakharov, I, Vizuete-Forster, M, Levine, M, Li, S, MacHugh, DE & Hill, EW 2006, 'Evidence for biogeographic patterning of mitochondrial DNA sequences in Eastern horse populations', Animal Genetics, vol. 37, no. 5, pp. 494-497. https://doi.org/10.1111/j.1365-2052.2006.01495.x

Evidence for biogeographic patterning of mitochondrial DNA sequences in Eastern horse populations. / McGahern, A.; Bower, M. A.M.; Edwards, C. J.; Brophy, P. O.; Sulimova, G.; Zakharov, I.; Vizuete-Forster, M.; Levine, M.; Li, S.; MacHugh, D. E.; Hill, E. W.

In: Animal Genetics, Vol. 37, No. 5, 01.10.2006, p. 494-497.

Research output: Contribution to journalArticle

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