Exceptionally strong intermolecular association in hydrophobic DNA minor groove binders and their potential therapeutic consequences

John A. Parkinson, Fraser J. Scott, Colin J. Suckling, Gail Wilson

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


An antibacterial DNA minor groove binder is shown by NOE experiments to self-associate in aqueous solution at temperatures up to 80 °C in an anti-parallel, head-to-tail orientation as found in binding to duplex DNA oligomers.
Original languageEnglish
Pages (from-to)1105-1108
Number of pages4
Issue number7
Publication statusPublished - 1 Jan 2013
Externally publishedYes

Cite this