TY - JOUR
T1 - Expedient synthesis of highly substituted 3,4-dihydro-1,2-oxathiine 2,2-dioxides and 1,2-oxathiine 2,2-dioxides
T2 - Revisiting sulfene additions to enaminoketones
AU - Aiken, Stuart
AU - Anozie, Kelechi
AU - De Azevedo, Orlando
AU - Cowan, Lewis
AU - Edgar, Ross
AU - Gabbutt, Christopher
AU - Heron, Bernard
AU - Lawrence, Pippa
AU - Mills, Abby
AU - Rice, Craig
AU - Urquhart, Mike
AU - Zonidis, Dimitrios
PY - 2019/11
Y1 - 2019/11
N2 - Diversely substituted 1,2-oxathiine 2,2-dioxides, including 3,5,6-triaryl-, 3,6-diaryl-, 3,5-diaryl-, 5,6-diaryl- and selected fused heterocyclic analogues, have been efficiently obtained by the application of a mild Cope elimination of a 4-amino moiety from the requisite 4-amino-3,4-dihydro-1,2-oxathiine 2,2-dioxides, which themselves were readily obtained by the addition of sulfenes to enaminoketones.
AB - Diversely substituted 1,2-oxathiine 2,2-dioxides, including 3,5,6-triaryl-, 3,6-diaryl-, 3,5-diaryl-, 5,6-diaryl- and selected fused heterocyclic analogues, have been efficiently obtained by the application of a mild Cope elimination of a 4-amino moiety from the requisite 4-amino-3,4-dihydro-1,2-oxathiine 2,2-dioxides, which themselves were readily obtained by the addition of sulfenes to enaminoketones.
UR - http://www.scopus.com/inward/record.url?scp=85074961739&partnerID=8YFLogxK
U2 - 10.1039/C9OB01657K
DO - 10.1039/C9OB01657K
M3 - Article
VL - 17
SP - 9585
EP - 9604
JO - Organic and Biomolecular Chemistry
JF - Organic and Biomolecular Chemistry
SN - 1477-0520
IS - 44
ER -