Factors Affecting Warfarin-Related Knowledge and INR Control of Patients Attending Physician- and Pharmacist-Managed Anticoagulation Clinics

Syed S. Hasan, R. Shamala, Imran A. Syed, N. Basariah, David W.K. Chong, Teh K. Mei, Ong H. Chin

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Objectives: To assess the anticoagulation knowledge and international normalized ratio (INR) control among patients on warfarin. Methods: A cross-sectional study with 156 randomly sampled patients from physician- (non-medication therapy adherence clinic [non-MTAC]) and pharmacist (MTAC)-run anticoagulation clinics using a validated interviewer-administered questionnaire. Patients' INR readings from 2008 to 2010 were recorded. Results: Patients on warfarin scored an average of 66.5% ± 36.0% for their knowledge on how warfarin works, 42.9% ± 44.9% for interaction between warfarin and alcohol, and 49.2% ± 21.1% for adverse effects. No significant differences were found between MTAC and non-MTAC patients on their knowledge. There was a negative correlation between patients' knowledge and age (P =.001, rs = .293) and a positive correlation between patients' knowledge and education level (P =.001, rs =.365). MTAC patients were found to have better INR control than non-MTAC when compared for mean percentage days in range (63.4% ± 18.9% vs 52.5% ± 18.2%; P =.006) and mean percentage visits in range (58.8% ± 17.9% vs 46.8% ± 18.6%; P =.001). Conclusions: MTAC patients were found to have better INR control compared to non-MTAC patients. A joint cooperation between physicians, pharmacists, and nurses should exist to achieve desired therapeutic outcomes.

LanguageEnglish
Pages485-493
Number of pages9
JournalJournal of Pharmacy Practice
Volume24
Issue number5
Early online date15 Aug 2011
DOIs
Publication statusPublished - Oct 2011
Externally publishedYes

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International Normalized Ratio
Warfarin
Pharmacists
Physicians
Medication Adherence
Therapeutics
Patient Education
Reading
Cross-Sectional Studies
Nurses
Interviews

Cite this

Hasan, Syed S. ; Shamala, R. ; Syed, Imran A. ; Basariah, N. ; Chong, David W.K. ; Mei, Teh K. ; Chin, Ong H. / Factors Affecting Warfarin-Related Knowledge and INR Control of Patients Attending Physician- and Pharmacist-Managed Anticoagulation Clinics. In: Journal of Pharmacy Practice. 2011 ; Vol. 24, No. 5. pp. 485-493.
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abstract = "Objectives: To assess the anticoagulation knowledge and international normalized ratio (INR) control among patients on warfarin. Methods: A cross-sectional study with 156 randomly sampled patients from physician- (non-medication therapy adherence clinic [non-MTAC]) and pharmacist (MTAC)-run anticoagulation clinics using a validated interviewer-administered questionnaire. Patients' INR readings from 2008 to 2010 were recorded. Results: Patients on warfarin scored an average of 66.5{\%} ± 36.0{\%} for their knowledge on how warfarin works, 42.9{\%} ± 44.9{\%} for interaction between warfarin and alcohol, and 49.2{\%} ± 21.1{\%} for adverse effects. No significant differences were found between MTAC and non-MTAC patients on their knowledge. There was a negative correlation between patients' knowledge and age (P =.001, rs = .293) and a positive correlation between patients' knowledge and education level (P =.001, rs =.365). MTAC patients were found to have better INR control than non-MTAC when compared for mean percentage days in range (63.4{\%} ± 18.9{\%} vs 52.5{\%} ± 18.2{\%}; P =.006) and mean percentage visits in range (58.8{\%} ± 17.9{\%} vs 46.8{\%} ± 18.6{\%}; P =.001). Conclusions: MTAC patients were found to have better INR control compared to non-MTAC patients. A joint cooperation between physicians, pharmacists, and nurses should exist to achieve desired therapeutic outcomes.",
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Factors Affecting Warfarin-Related Knowledge and INR Control of Patients Attending Physician- and Pharmacist-Managed Anticoagulation Clinics. / Hasan, Syed S.; Shamala, R.; Syed, Imran A.; Basariah, N.; Chong, David W.K.; Mei, Teh K.; Chin, Ong H.

In: Journal of Pharmacy Practice, Vol. 24, No. 5, 10.2011, p. 485-493.

Research output: Contribution to journalArticle

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