Factors influencing adherence to antiretroviral treatment in Asian developing countries: a systematic review

Sharada P. Wasti; Edwin Van Teijlingen; Padam Simkhada; Julian Randall; Susan Baxter; Pamela Kirkpatrick; Vijay S. GC

doi:10.1111/j.1365-3156.2011.02888.x

Factors influencing adherence to antiretroviral treatment in Asian developing countries: a systematic review

Sharada P. Wasti, Edwin Van Teijlingen, Padam Simkhada, Julian Randall, Susan Baxter, Pamela Kirkpatrick, Vijay S. GC

Research output: Contribution to journal › Review article › peer-review

65 Citations (Scopus)

Abstract

Objective: To systematically review the literature of factors affecting adherence to Antiretroviral treatment (ART) in Asian developing countries.

Methods Database searches in Medline⁄Ovid, Cochrane library, CINAHL, Scopus and PsychINFO for studies published between 1996 and December 2010. The reference lists of included papers were also checked, with citation searching on key papers.

Results: A total of 437 studies were identified, and 18 articles met the inclusion criteria and were extracted and critically appraised, representing in 12 quantitative, four qualitative and two mixed-method studies. Twenty-two individual themes, including financial difficulties, side effects, access,stigma and discrimination, simply forgetting and being too busy, impeded adherence to ART, and 11 themes, including family support, self-efficacy and desire to live longer, facilitated adherence.

Conclusion: Adherence to ART varies between individuals and over time. We need to redress impeding factors while promoting factors that reinforce adherence through financial support, better accessible points for medicine refills, consulting doctors for help with side effects, social support and trusting relationships with care providers.

Original language	English
Pages (from-to)	71-81
Number of pages	11
Journal	Tropical Medicine and International Health
Volume	17
Issue number	1
Early online date	3 Oct 2011
DOIs	https://doi.org/10.1111/j.1365-3156.2011.02888.x
Publication status	Published - Jan 2012
Externally published	Yes

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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title = "Factors influencing adherence to antiretroviral treatment in Asian developing countries: a systematic review",

abstract = "Objective: To systematically review the literature of factors affecting adherence to Antiretroviral treatment (ART) in Asian developing countries. Methods Database searches in Medline⁄Ovid, Cochrane library, CINAHL, Scopus and PsychINFO for studies published between 1996 and December 2010. The reference lists of included papers were also checked, with citation searching on key papers.Results: A total of 437 studies were identified, and 18 articles met the inclusion criteria and were extracted and critically appraised, representing in 12 quantitative, four qualitative and two mixed-method studies. Twenty-two individual themes, including financial difficulties, side effects, access,stigma and discrimination, simply forgetting and being too busy, impeded adherence to ART, and 11 themes, including family support, self-efficacy and desire to live longer, facilitated adherence.Conclusion: Adherence to ART varies between individuals and over time. We need to redress impeding factors while promoting factors that reinforce adherence through financial support, better accessible points for medicine refills, consulting doctors for help with side effects, social support and trusting relationships with care providers.",

keywords = "HIV/⁄AIDS, antiretroviral treatment, adherence, barrier, facilitator, Asia",

author = "Wasti, \{Sharada P.\} and \{Van Teijlingen\}, Edwin and Padam Simkhada and Julian Randall and Susan Baxter and Pamela Kirkpatrick and GC, \{Vijay S.\}",

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doi = "10.1111/j.1365-3156.2011.02888.x",

language = "English",

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T1 - Factors influencing adherence to antiretroviral treatment in Asian developing countries

T2 - a systematic review

AU - Wasti, Sharada P.

AU - Van Teijlingen, Edwin

AU - Simkhada, Padam

AU - Randall, Julian

AU - Baxter, Susan

AU - Kirkpatrick, Pamela

AU - GC, Vijay S.

PY - 2012/1

Y1 - 2012/1

N2 - Objective: To systematically review the literature of factors affecting adherence to Antiretroviral treatment (ART) in Asian developing countries. Methods Database searches in Medline⁄Ovid, Cochrane library, CINAHL, Scopus and PsychINFO for studies published between 1996 and December 2010. The reference lists of included papers were also checked, with citation searching on key papers.Results: A total of 437 studies were identified, and 18 articles met the inclusion criteria and were extracted and critically appraised, representing in 12 quantitative, four qualitative and two mixed-method studies. Twenty-two individual themes, including financial difficulties, side effects, access,stigma and discrimination, simply forgetting and being too busy, impeded adherence to ART, and 11 themes, including family support, self-efficacy and desire to live longer, facilitated adherence.Conclusion: Adherence to ART varies between individuals and over time. We need to redress impeding factors while promoting factors that reinforce adherence through financial support, better accessible points for medicine refills, consulting doctors for help with side effects, social support and trusting relationships with care providers.

AB - Objective: To systematically review the literature of factors affecting adherence to Antiretroviral treatment (ART) in Asian developing countries. Methods Database searches in Medline⁄Ovid, Cochrane library, CINAHL, Scopus and PsychINFO for studies published between 1996 and December 2010. The reference lists of included papers were also checked, with citation searching on key papers.Results: A total of 437 studies were identified, and 18 articles met the inclusion criteria and were extracted and critically appraised, representing in 12 quantitative, four qualitative and two mixed-method studies. Twenty-two individual themes, including financial difficulties, side effects, access,stigma and discrimination, simply forgetting and being too busy, impeded adherence to ART, and 11 themes, including family support, self-efficacy and desire to live longer, facilitated adherence.Conclusion: Adherence to ART varies between individuals and over time. We need to redress impeding factors while promoting factors that reinforce adherence through financial support, better accessible points for medicine refills, consulting doctors for help with side effects, social support and trusting relationships with care providers.

KW - HIV/⁄AIDS

KW - antiretroviral treatment

KW - adherence

KW - barrier

KW - facilitator

KW - Asia

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DO - 10.1111/j.1365-3156.2011.02888.x

M3 - Review article

C2 - 21967241

AN - SCOPUS:84155163121

SN - 1360-2276

VL - 17

SP - 71

EP - 81

JO - Tropical Medicine and International Health

JF - Tropical Medicine and International Health

IS - 1

ER -

Factors influencing adherence to antiretroviral treatment in Asian developing countries: a systematic review

Abstract

UN SDGs

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