Fatty acid and sterol metabolism: Potential antimicrobial targets in apicomplexan and trypanosomatid parasitic protozoa

Agriculture & Biology

• Trypanosomatidae 100%
• sterols 75%
• Protozoa 73%
• anti-infective agents 60%
• fatty acids 54%
• metabolism 46%
• parasites 40%
• biosynthesis 25%
• Leishmania 22%
• squalene monooxygenase 15%
• triclosan 14%
• azoles 13%
• triazoles 12%
• Trypanosoma brucei 12%
• Plasmodium falciparum 11%
• ergosterol 11%
• drug resistance 11%
• Toxoplasma gondii 11%
• Trypanosoma 10%
• transferases 9%
• plastids 9%
• biochemical pathways 8%
• therapeutics 7%
• mammals 7%
• toxicity 6%
• drugs 6%
• fungi 5%
• synthesis 5%

Medicine & Life Sciences

• Sterols 91%
• Fatty Acids 67%
• Parasites 49%
• thiolactomycin 39%
• Leishmania 22%
• epoxidase 19%
• N-dodecyl-L-lysine amide 16%
• Plastids 15%
• Squalene 14%
• Triclosan 14%
• Ergosterol 14%
• Myristic Acid 13%
• Terbinafine 13%
• Triazoles 13%
• Trypanosoma brucei brucei 12%
• Azoles 12%
• Trypanosoma 12%
• Biosynthetic Pathways 11%
• Drug Design 11%
• Cytostatic Agents 11%
• Toxoplasma 11%
• Life Cycle Stages 10%
• Plasmodium falciparum 10%
• Transferases 10%
• Anti-Infective Agents 10%
• Growth 9%
• Drug Resistance 9%
• Fungi 8%
• Mammals 8%
• Therapeutics 6%