Flexible access to conformationally-locked bicyclic morpholines

Rachael Bogacki; Duncan M. Gill; William J. Kerr; Scott Lamont; John A. Parkinson; Laura C. Paterson

doi:10.1039/c3cc45627g

Flexible access to conformationally-locked bicyclic morpholines

Rachael Bogacki, Duncan M. Gill, William J. Kerr, Scott Lamont, John A. Parkinson, Laura C. Paterson

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

A preparatively accessible route to a series of conformationally-locked bicyclic morpholines has been developed. This flexible approach allows for diversification in order for a small array of lead-like scaffolds to be synthesised from readily available key building blocks.

Original language	English
Pages (from-to)	8931-8933
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	79
Early online date	15 Aug 2013
DOIs	https://doi.org/10.1039/c3cc45627g
Publication status	Published - 11 Oct 2013

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title = "Flexible access to conformationally-locked bicyclic morpholines",

abstract = "A preparatively accessible route to a series of conformationally-locked bicyclic morpholines has been developed. This flexible approach allows for diversification in order for a small array of lead-like scaffolds to be synthesised from readily available key building blocks.",

author = "Rachael Bogacki and Gill, {Duncan M.} and Kerr, {William J.} and Scott Lamont and Parkinson, {John A.} and Paterson, {Laura C.}",

year = "2013",

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T1 - Flexible access to conformationally-locked bicyclic morpholines

AU - Bogacki, Rachael

AU - Gill, Duncan M.

AU - Kerr, William J.

AU - Lamont, Scott

AU - Parkinson, John A.

AU - Paterson, Laura C.

PY - 2013/10/11

Y1 - 2013/10/11

N2 - A preparatively accessible route to a series of conformationally-locked bicyclic morpholines has been developed. This flexible approach allows for diversification in order for a small array of lead-like scaffolds to be synthesised from readily available key building blocks.

AB - A preparatively accessible route to a series of conformationally-locked bicyclic morpholines has been developed. This flexible approach allows for diversification in order for a small array of lead-like scaffolds to be synthesised from readily available key building blocks.

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U2 - 10.1039/c3cc45627g

DO - 10.1039/c3cc45627g

M3 - Article

C2 - 23963244

AN - SCOPUS:84883856551

SN - 1359-7345

VL - 49

SP - 8931

EP - 8933

JO - Chemical Communications

JF - Chemical Communications

IS - 79

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Flexible access to conformationally-locked bicyclic morpholines

Abstract

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