Flow of Cells in Microchannels

Y. F. Yap, D. Li, J. C. Chai

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

This article investigates the motion of a cell in a carrier fluid flowing along a twodimensional channel. The cell, assumed elliptical, is modeled as a highly viscous fluid with rigid body motion. A fixed grid approach is used. A combined formulation with one set of governing equations to treat both phases is employed. The cell-fluid interface is tracked by a distance function. The finite volume method is employed to solve the governing equations. For demonstration purpose, the result for the flow of a single elliptical cell in an obstructed channel is presented.

Original languageEnglish
Pages (from-to)448-453
Number of pages6
JournalJournal of Physics: Conference Series
Volume34
Issue number1
DOIs
Publication statusPublished - 2006
Externally publishedYes

Fingerprint

microchannels
cells
fluids
finite volume method
viscous fluids
rigid structures
grids
formulations

Cite this

Yap, Y. F. ; Li, D. ; Chai, J. C. / Flow of Cells in Microchannels. In: Journal of Physics: Conference Series. 2006 ; Vol. 34, No. 1. pp. 448-453.
@article{0183c89348a04d81bd1dd73b5e98028f,
title = "Flow of Cells in Microchannels",
abstract = "This article investigates the motion of a cell in a carrier fluid flowing along a twodimensional channel. The cell, assumed elliptical, is modeled as a highly viscous fluid with rigid body motion. A fixed grid approach is used. A combined formulation with one set of governing equations to treat both phases is employed. The cell-fluid interface is tracked by a distance function. The finite volume method is employed to solve the governing equations. For demonstration purpose, the result for the flow of a single elliptical cell in an obstructed channel is presented.",
keywords = "Cell motion",
author = "Yap, {Y. F.} and D. Li and Chai, {J. C.}",
year = "2006",
doi = "10.1088/1742-6596/34/1/073",
language = "English",
volume = "34",
pages = "448--453",
journal = "Journal of Physics: Conference Series",
issn = "1742-6588",
publisher = "IOP Publishing Ltd.",
number = "1",

}

Flow of Cells in Microchannels. / Yap, Y. F.; Li, D.; Chai, J. C.

In: Journal of Physics: Conference Series, Vol. 34, No. 1, 2006, p. 448-453.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Flow of Cells in Microchannels

AU - Yap, Y. F.

AU - Li, D.

AU - Chai, J. C.

PY - 2006

Y1 - 2006

N2 - This article investigates the motion of a cell in a carrier fluid flowing along a twodimensional channel. The cell, assumed elliptical, is modeled as a highly viscous fluid with rigid body motion. A fixed grid approach is used. A combined formulation with one set of governing equations to treat both phases is employed. The cell-fluid interface is tracked by a distance function. The finite volume method is employed to solve the governing equations. For demonstration purpose, the result for the flow of a single elliptical cell in an obstructed channel is presented.

AB - This article investigates the motion of a cell in a carrier fluid flowing along a twodimensional channel. The cell, assumed elliptical, is modeled as a highly viscous fluid with rigid body motion. A fixed grid approach is used. A combined formulation with one set of governing equations to treat both phases is employed. The cell-fluid interface is tracked by a distance function. The finite volume method is employed to solve the governing equations. For demonstration purpose, the result for the flow of a single elliptical cell in an obstructed channel is presented.

KW - Cell motion

UR - http://www.scopus.com/inward/record.url?scp=33744540750&partnerID=8YFLogxK

U2 - 10.1088/1742-6596/34/1/073

DO - 10.1088/1742-6596/34/1/073

M3 - Article

VL - 34

SP - 448

EP - 453

JO - Journal of Physics: Conference Series

JF - Journal of Physics: Conference Series

SN - 1742-6588

IS - 1

ER -