Flow visualization within a Ventricular Inhaler Device using Open Source CFD for Performance Enhancement

Noukhez Ahmed, Taimoor Asim, Rakesh Mishra, Blaise Nsom

Research output: Contribution to journalArticle

Abstract

A Ventricular Inhaler Device (VID) is used as a quick-relief medication for treating wheezing and shortness of breath. VID uses Albuterol (a bronchodilator) to relax muscles and open airways. The flow distribution of Albuterol within the VID is the primary parameter that dictates the performance of the device. Poorly designed VIDs can cause accumulation of Albuterol in outlet section of the device, causing flow blockages, which lead to inefficient performance of the device and inappropriate drug delivery. In the present study, Computational Fluid Dynamics (CFD) based advanced techniques have been used in order to visualize the complex flow behavior within a conventional VID, with a purpose to enhance the performance of the device. It has been observed that the pressure coefficient within the injector and outlet duct remains constant, while it decreases in the cyclone separator. Thus, the inlet flow velocity has been seen to have dominating effect on the performance of the VID compared to the rotational velocity of the blades. It has been further noticed that as the flow rate of the drug increases, the efficiency of VID also decreases to a minimum value, after which it remains constant. Moreover, lower rotational speeds of the blades increase the efficiency of the device at higher drug flow rates.
Original languageEnglish
Pages (from-to)21-26
Number of pages6
JournalInternational Journal of COMADEM
Volume22
Issue number2
Publication statusPublished - 2 Aug 2019

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Albuterol
Flow visualization
Computational fluid dynamics
Flow rate
Cyclone separators
Inlet flow
Drug delivery
Flow velocity
Ducts
Muscle
Bronchodilator Agents
Pharmaceutical Preparations
Open source
Visualization
Enhancement
Drugs

Cite this

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title = "Flow visualization within a Ventricular Inhaler Device using Open Source CFD for Performance Enhancement",
abstract = "A Ventricular Inhaler Device (VID) is used as a quick-relief medication for treating wheezing and shortness of breath. VID uses Albuterol (a bronchodilator) to relax muscles and open airways. The flow distribution of Albuterol within the VID is the primary parameter that dictates the performance of the device. Poorly designed VIDs can cause accumulation of Albuterol in outlet section of the device, causing flow blockages, which lead to inefficient performance of the device and inappropriate drug delivery. In the present study, Computational Fluid Dynamics (CFD) based advanced techniques have been used in order to visualize the complex flow behavior within a conventional VID, with a purpose to enhance the performance of the device. It has been observed that the pressure coefficient within the injector and outlet duct remains constant, while it decreases in the cyclone separator. Thus, the inlet flow velocity has been seen to have dominating effect on the performance of the VID compared to the rotational velocity of the blades. It has been further noticed that as the flow rate of the drug increases, the efficiency of VID also decreases to a minimum value, after which it remains constant. Moreover, lower rotational speeds of the blades increase the efficiency of the device at higher drug flow rates.",
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Flow visualization within a Ventricular Inhaler Device using Open Source CFD for Performance Enhancement. / Ahmed, Noukhez; Asim, Taimoor; Mishra, Rakesh; Nsom, Blaise.

In: International Journal of COMADEM, Vol. 22, No. 2, 02.08.2019, p. 21-26.

Research output: Contribution to journalArticle

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T1 - Flow visualization within a Ventricular Inhaler Device using Open Source CFD for Performance Enhancement

AU - Ahmed, Noukhez

AU - Asim, Taimoor

AU - Mishra, Rakesh

AU - Nsom, Blaise

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N2 - A Ventricular Inhaler Device (VID) is used as a quick-relief medication for treating wheezing and shortness of breath. VID uses Albuterol (a bronchodilator) to relax muscles and open airways. The flow distribution of Albuterol within the VID is the primary parameter that dictates the performance of the device. Poorly designed VIDs can cause accumulation of Albuterol in outlet section of the device, causing flow blockages, which lead to inefficient performance of the device and inappropriate drug delivery. In the present study, Computational Fluid Dynamics (CFD) based advanced techniques have been used in order to visualize the complex flow behavior within a conventional VID, with a purpose to enhance the performance of the device. It has been observed that the pressure coefficient within the injector and outlet duct remains constant, while it decreases in the cyclone separator. Thus, the inlet flow velocity has been seen to have dominating effect on the performance of the VID compared to the rotational velocity of the blades. It has been further noticed that as the flow rate of the drug increases, the efficiency of VID also decreases to a minimum value, after which it remains constant. Moreover, lower rotational speeds of the blades increase the efficiency of the device at higher drug flow rates.

AB - A Ventricular Inhaler Device (VID) is used as a quick-relief medication for treating wheezing and shortness of breath. VID uses Albuterol (a bronchodilator) to relax muscles and open airways. The flow distribution of Albuterol within the VID is the primary parameter that dictates the performance of the device. Poorly designed VIDs can cause accumulation of Albuterol in outlet section of the device, causing flow blockages, which lead to inefficient performance of the device and inappropriate drug delivery. In the present study, Computational Fluid Dynamics (CFD) based advanced techniques have been used in order to visualize the complex flow behavior within a conventional VID, with a purpose to enhance the performance of the device. It has been observed that the pressure coefficient within the injector and outlet duct remains constant, while it decreases in the cyclone separator. Thus, the inlet flow velocity has been seen to have dominating effect on the performance of the VID compared to the rotational velocity of the blades. It has been further noticed that as the flow rate of the drug increases, the efficiency of VID also decreases to a minimum value, after which it remains constant. Moreover, lower rotational speeds of the blades increase the efficiency of the device at higher drug flow rates.

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