General acid catalysed hydrolysis of β-sultams involves nucleophilic catalysis

Nicholas J. Baxter, Andrew P. Laws, Laurent J.H. Rigoreau, Michael I. Page

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The hydrolysis of the four-membered ring sulfonamide N-benzyl β-sultam is catalysed by carboxylic acids, which is attributed to specific acid- nucleophilic catalysis with the intermediate formation of a mixed anhydride which can be trapped with aniline.

Original languageEnglish
Pages (from-to)2401-2402
Number of pages2
JournalChemical Communications
Issue number23
DOIs
Publication statusPublished - 7 Dec 1999

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    Baxter, N. J., Laws, A. P., Rigoreau, L. J. H., & Page, M. I. (1999). General acid catalysed hydrolysis of β-sultams involves nucleophilic catalysis. Chemical Communications, (23), 2401-2402. https://doi.org/10.1039/a907501a