General acid catalysed hydrolysis of β-sultams involves nucleophilic catalysis

Nicholas J. Baxter, Andrew P. Laws, Laurent J.H. Rigoreau, Michael I. Page

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The hydrolysis of the four-membered ring sulfonamide N-benzyl β-sultam is catalysed by carboxylic acids, which is attributed to specific acid- nucleophilic catalysis with the intermediate formation of a mixed anhydride which can be trapped with aniline.

Original languageEnglish
Pages (from-to)2401-2402
Number of pages2
JournalChemical Communications
Issue number23
DOIs
Publication statusPublished - 7 Dec 1999

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Anhydrides
Sulfonamides
Aniline
Carboxylic Acids
Carboxylic acids
Catalysis
Hydrolysis
Acids
aniline
naphthosultone

Cite this

Baxter, Nicholas J. ; Laws, Andrew P. ; Rigoreau, Laurent J.H. ; Page, Michael I. / General acid catalysed hydrolysis of β-sultams involves nucleophilic catalysis. In: Chemical Communications. 1999 ; No. 23. pp. 2401-2402.
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General acid catalysed hydrolysis of β-sultams involves nucleophilic catalysis. / Baxter, Nicholas J.; Laws, Andrew P.; Rigoreau, Laurent J.H.; Page, Michael I.

In: Chemical Communications, No. 23, 07.12.1999, p. 2401-2402.

Research output: Contribution to journalArticle

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