Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle

Stephen Park, David A. Magee, Paul McGettigan, Matthew Teasdale, Ceiridwen Edwards, Amanda Lohan, Alison Murphy, Martin Braud, Mark Donoghue, Yuan Liu, Andrew Chamberlain, Kévin Rue-Albrecht, Steven Shroeder, Charles Spillane, Shuaishuai Tai, Daniel Bradley, Tad Sonstegard, Brendan Loftus, David MacHugh

Research output: Contribution to journalArticle

69 Citations (Scopus)

Abstract

Domestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus. While previous genetic studies have shed some light on the evolutionary relationships between European aurochs and modern cattle, important questions remain unanswered, including the phylogenetic status of aurochs, whether gene flow from aurochs into early domestic populations occurred, and which genomic regions were subject to selection processes during and after domestication. Here, we address these questions using whole-genome sequencing data generated from an approximately 6,750-year-old British aurochs bone and genome sequence data from 81 additional cattle plus genome-wide single nucleotide polymorphism data from a diverse panel of 1,225 modern animals.
LanguageEnglish
Number of pages15
JournalGenome Biology
Volume16
Issue number234
DOIs
Publication statusPublished - 26 Oct 2015
Externally publishedYes

Fingerprint

Phylogeography
phylogeography
cattle
genome
domestication
Genome
Gene Flow
Patient Selection
gene flow
Single Nucleotide Polymorphism
bone
genomics
polymorphism
single nucleotide polymorphism
phylogenetics
Bone and Bones
animal
bones
Population
phylogeny

Cite this

Park, Stephen ; Magee, David A. ; McGettigan, Paul ; Teasdale, Matthew ; Edwards, Ceiridwen ; Lohan, Amanda ; Murphy, Alison ; Braud, Martin ; Donoghue, Mark ; Liu, Yuan ; Chamberlain, Andrew ; Rue-Albrecht, Kévin ; Shroeder, Steven ; Spillane, Charles ; Tai, Shuaishuai ; Bradley, Daniel ; Sonstegard, Tad ; Loftus, Brendan ; MacHugh, David. / Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle. In: Genome Biology. 2015 ; Vol. 16, No. 234.
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abstract = "Domestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus. While previous genetic studies have shed some light on the evolutionary relationships between European aurochs and modern cattle, important questions remain unanswered, including the phylogenetic status of aurochs, whether gene flow from aurochs into early domestic populations occurred, and which genomic regions were subject to selection processes during and after domestication. Here, we address these questions using whole-genome sequencing data generated from an approximately 6,750-year-old British aurochs bone and genome sequence data from 81 additional cattle plus genome-wide single nucleotide polymorphism data from a diverse panel of 1,225 modern animals.",
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author = "Stephen Park and Magee, {David A.} and Paul McGettigan and Matthew Teasdale and Ceiridwen Edwards and Amanda Lohan and Alison Murphy and Martin Braud and Mark Donoghue and Yuan Liu and Andrew Chamberlain and K{\'e}vin Rue-Albrecht and Steven Shroeder and Charles Spillane and Shuaishuai Tai and Daniel Bradley and Tad Sonstegard and Brendan Loftus and David MacHugh",
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Park, S, Magee, DA, McGettigan, P, Teasdale, M, Edwards, C, Lohan, A, Murphy, A, Braud, M, Donoghue, M, Liu, Y, Chamberlain, A, Rue-Albrecht, K, Shroeder, S, Spillane, C, Tai, S, Bradley, D, Sonstegard, T, Loftus, B & MacHugh, D 2015, 'Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle', Genome Biology, vol. 16, no. 234. https://doi.org/10.1186/s13059-015-0790-2

Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle. / Park, Stephen; Magee, David A.; McGettigan, Paul; Teasdale, Matthew; Edwards, Ceiridwen; Lohan, Amanda; Murphy, Alison; Braud, Martin; Donoghue, Mark; Liu, Yuan; Chamberlain, Andrew; Rue-Albrecht, Kévin; Shroeder, Steven; Spillane, Charles; Tai, Shuaishuai; Bradley, Daniel; Sonstegard, Tad; Loftus, Brendan; MacHugh, David.

In: Genome Biology, Vol. 16, No. 234, 26.10.2015.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle

AU - Park, Stephen

AU - Magee, David A.

AU - McGettigan, Paul

AU - Teasdale, Matthew

AU - Edwards, Ceiridwen

AU - Lohan, Amanda

AU - Murphy, Alison

AU - Braud, Martin

AU - Donoghue, Mark

AU - Liu, Yuan

AU - Chamberlain, Andrew

AU - Rue-Albrecht, Kévin

AU - Shroeder, Steven

AU - Spillane, Charles

AU - Tai, Shuaishuai

AU - Bradley, Daniel

AU - Sonstegard, Tad

AU - Loftus, Brendan

AU - MacHugh, David

PY - 2015/10/26

Y1 - 2015/10/26

N2 - Domestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus. While previous genetic studies have shed some light on the evolutionary relationships between European aurochs and modern cattle, important questions remain unanswered, including the phylogenetic status of aurochs, whether gene flow from aurochs into early domestic populations occurred, and which genomic regions were subject to selection processes during and after domestication. Here, we address these questions using whole-genome sequencing data generated from an approximately 6,750-year-old British aurochs bone and genome sequence data from 81 additional cattle plus genome-wide single nucleotide polymorphism data from a diverse panel of 1,225 modern animals.

AB - Domestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus. While previous genetic studies have shed some light on the evolutionary relationships between European aurochs and modern cattle, important questions remain unanswered, including the phylogenetic status of aurochs, whether gene flow from aurochs into early domestic populations occurred, and which genomic regions were subject to selection processes during and after domestication. Here, we address these questions using whole-genome sequencing data generated from an approximately 6,750-year-old British aurochs bone and genome sequence data from 81 additional cattle plus genome-wide single nucleotide polymorphism data from a diverse panel of 1,225 modern animals.

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KW - Aurochs

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KW - Cattle

KW - Domestication

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KW - Genome

KW - Hybridization

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DO - 10.1186/s13059-015-0790-2

M3 - Article

VL - 16

JO - Genome Biology

T2 - Genome Biology

JF - Genome Biology

SN - 1474-7596

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ER -