Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle

Stephen Park, David A. Magee, Paul McGettigan, Matthew Teasdale, Ceiridwen Edwards, Amanda Lohan, Alison Murphy, Martin Braud, Mark Donoghue, Yuan Liu, Andrew Chamberlain, Kévin Rue-Albrecht, Steven Shroeder, Charles Spillane, Shuaishuai Tai, Daniel Bradley, Tad Sonstegard, Brendan Loftus, David MacHugh

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79 Citations (Scopus)

Abstract

Domestication of the now-extinct wild aurochs, Bos primigenius, gave rise to the two major domestic extant cattle taxa, B. taurus and B. indicus. While previous genetic studies have shed some light on the evolutionary relationships between European aurochs and modern cattle, important questions remain unanswered, including the phylogenetic status of aurochs, whether gene flow from aurochs into early domestic populations occurred, and which genomic regions were subject to selection processes during and after domestication. Here, we address these questions using whole-genome sequencing data generated from an approximately 6,750-year-old British aurochs bone and genome sequence data from 81 additional cattle plus genome-wide single nucleotide polymorphism data from a diverse panel of 1,225 modern animals.
Original languageEnglish
Number of pages15
JournalGenome Biology
Volume16
Issue number234
DOIs
Publication statusPublished - 26 Oct 2015
Externally publishedYes

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    Park, S., Magee, D. A., McGettigan, P., Teasdale, M., Edwards, C., Lohan, A., Murphy, A., Braud, M., Donoghue, M., Liu, Y., Chamberlain, A., Rue-Albrecht, K., Shroeder, S., Spillane, C., Tai, S., Bradley, D., Sonstegard, T., Loftus, B., & MacHugh, D. (2015). Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle. Genome Biology, 16(234). https://doi.org/10.1186/s13059-015-0790-2