Hand sanitisers amid CoViD-19: A critical review of alcohol-based products on the market and formulation approaches to respond to increasing demand.

Alberto Beradi, Diego Perinelli, Hamid Merchant, Lorina Bisharat, Iman Basheti, Giulia Bonacucina, Marco Cespi, Giovanni Palmieri

Research output: Contribution to journalReview article

11 Citations (Scopus)

Abstract

The world is facing a medical crisis amid the CoViD-19 pandemic and the role of adequate hygiene and hand sanitisers is inevitable in controlling the spread of infection in public places and healthcare institutions. There has been a great surge in demand for hand sanitisation products leading to shortages in their supply. A consequent increase of substandard products in the market has raised safety concerns. This article, therefore, presents a critical review of hand sanitation approaches and products available on the market in light of the scientific evidence available to date. This review also provides a range of hand sanitisation product formulations, and manufacturing instructions to allow for extemporaneous preparations at the community and hospital pharmacies during this urgent crisis. In addition, this emergent situation is expected to continue, hence hand sanitisers will be in demand for an extended time, and the availability and purchase of substandard products on the market create an ongoing safety concern. Therefore, this article shall also provide various commercial organisations, interested in stepping forward the production and marketing of hand sanitisers, with a guide on the development of products of standardised ingredients and formulations.
Original languageEnglish
Article number119431
Number of pages14
JournalInternational Journal of Pharmaceutics
Volume584
Early online date16 May 2020
DOIs
Publication statusPublished - 30 Jun 2020

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