Healthcare-associated infections (HCAIs): The magnitude of the problem

Martin Kiernan, David Leaper

Research output: Contribution to journalArticle

Abstract

Healthcare-associated infections (HCAIs) are an important and costly complication of healthcare throughout both primary and secondary sectors. In the European Union alone, the financial burden associated with HCAIs is up to €10b annually. HCAIs add unacceptable costs to healthcare economies – a 2- to 3-fold overall increase in the cost of the affected patient’s care in terms of extended hospital stay and associated costs. Increasing resistance following the use, mis-use, and over-use of antibiotics poses a world-wide problem that is compounded by the fact that no new antibiotics are in the pipeline. The recent and expanding appearance of carbapenemase resistance is of particular concern, as some strains of Klebsiella pneumoniae that produce carbapenemase are almost pan-resistant, meaning that antimicrobial therapy is virtually impossible. There is, however, good evidence that control measures can be effective. In the UK, the overall numbers of methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium difficile infections have fallen due to increased compliance with infection prevention/control procedures. In particular, the delivery of care bundles containing evidence-based interventions has proved highly effective in preventing MRSA bacteraemias along with the “clean-your-hands” campaign and other measures such as universal admission screening. Surgical site infection (SSI) is probably the most preventable HCAI, yet due to the inconsistent implementation of level 1A evidence-based interventions, the UK and US have shown disappointing failures to reduce SSI. The reason for this lack of progress in SSI likely reflects poor compliance with guidelines and checklists.
LanguageEnglish
Pages35-37
Number of pages3
JournalEWMA Journal
Volume14
Issue number2
Publication statusPublished - Oct 2014

Fingerprint

Cross Infection
Surgical Wound Infection
Methicillin-Resistant Staphylococcus aureus
Patient Care Bundles
Anti-Bacterial Agents
Clostridium Infections
Costs and Cost Analysis
Clostridium difficile
Klebsiella pneumoniae
European Union
Infection Control
Bacteremia
Checklist
Health Care Costs
Length of Stay
Patient Care
Hand
Guidelines
Delivery of Health Care
carbapenemase

Cite this

Kiernan, Martin ; Leaper, David. / Healthcare-associated infections (HCAIs) : The magnitude of the problem. In: EWMA Journal. 2014 ; Vol. 14, No. 2. pp. 35-37.
@article{5b9a0e49e13e4f70886fed67a383fc06,
title = "Healthcare-associated infections (HCAIs): The magnitude of the problem",
abstract = "Healthcare-associated infections (HCAIs) are an important and costly complication of healthcare throughout both primary and secondary sectors. In the European Union alone, the financial burden associated with HCAIs is up to €10b annually. HCAIs add unacceptable costs to healthcare economies – a 2- to 3-fold overall increase in the cost of the affected patient’s care in terms of extended hospital stay and associated costs. Increasing resistance following the use, mis-use, and over-use of antibiotics poses a world-wide problem that is compounded by the fact that no new antibiotics are in the pipeline. The recent and expanding appearance of carbapenemase resistance is of particular concern, as some strains of Klebsiella pneumoniae that produce carbapenemase are almost pan-resistant, meaning that antimicrobial therapy is virtually impossible. There is, however, good evidence that control measures can be effective. In the UK, the overall numbers of methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium difficile infections have fallen due to increased compliance with infection prevention/control procedures. In particular, the delivery of care bundles containing evidence-based interventions has proved highly effective in preventing MRSA bacteraemias along with the “clean-your-hands” campaign and other measures such as universal admission screening. Surgical site infection (SSI) is probably the most preventable HCAI, yet due to the inconsistent implementation of level 1A evidence-based interventions, the UK and US have shown disappointing failures to reduce SSI. The reason for this lack of progress in SSI likely reflects poor compliance with guidelines and checklists.",
keywords = "Healthcare associated infection",
author = "Martin Kiernan and David Leaper",
year = "2014",
month = "10",
language = "English",
volume = "14",
pages = "35--37",
journal = "EWMA Journal",
issn = "1609-2759",
publisher = "European Wound Management Association (EWMA)",
number = "2",

}

Kiernan, M & Leaper, D 2014, 'Healthcare-associated infections (HCAIs): The magnitude of the problem', EWMA Journal, vol. 14, no. 2, pp. 35-37.

Healthcare-associated infections (HCAIs) : The magnitude of the problem. / Kiernan, Martin; Leaper, David.

In: EWMA Journal, Vol. 14, No. 2, 10.2014, p. 35-37.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Healthcare-associated infections (HCAIs)

T2 - EWMA Journal

AU - Kiernan, Martin

AU - Leaper, David

PY - 2014/10

Y1 - 2014/10

N2 - Healthcare-associated infections (HCAIs) are an important and costly complication of healthcare throughout both primary and secondary sectors. In the European Union alone, the financial burden associated with HCAIs is up to €10b annually. HCAIs add unacceptable costs to healthcare economies – a 2- to 3-fold overall increase in the cost of the affected patient’s care in terms of extended hospital stay and associated costs. Increasing resistance following the use, mis-use, and over-use of antibiotics poses a world-wide problem that is compounded by the fact that no new antibiotics are in the pipeline. The recent and expanding appearance of carbapenemase resistance is of particular concern, as some strains of Klebsiella pneumoniae that produce carbapenemase are almost pan-resistant, meaning that antimicrobial therapy is virtually impossible. There is, however, good evidence that control measures can be effective. In the UK, the overall numbers of methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium difficile infections have fallen due to increased compliance with infection prevention/control procedures. In particular, the delivery of care bundles containing evidence-based interventions has proved highly effective in preventing MRSA bacteraemias along with the “clean-your-hands” campaign and other measures such as universal admission screening. Surgical site infection (SSI) is probably the most preventable HCAI, yet due to the inconsistent implementation of level 1A evidence-based interventions, the UK and US have shown disappointing failures to reduce SSI. The reason for this lack of progress in SSI likely reflects poor compliance with guidelines and checklists.

AB - Healthcare-associated infections (HCAIs) are an important and costly complication of healthcare throughout both primary and secondary sectors. In the European Union alone, the financial burden associated with HCAIs is up to €10b annually. HCAIs add unacceptable costs to healthcare economies – a 2- to 3-fold overall increase in the cost of the affected patient’s care in terms of extended hospital stay and associated costs. Increasing resistance following the use, mis-use, and over-use of antibiotics poses a world-wide problem that is compounded by the fact that no new antibiotics are in the pipeline. The recent and expanding appearance of carbapenemase resistance is of particular concern, as some strains of Klebsiella pneumoniae that produce carbapenemase are almost pan-resistant, meaning that antimicrobial therapy is virtually impossible. There is, however, good evidence that control measures can be effective. In the UK, the overall numbers of methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium difficile infections have fallen due to increased compliance with infection prevention/control procedures. In particular, the delivery of care bundles containing evidence-based interventions has proved highly effective in preventing MRSA bacteraemias along with the “clean-your-hands” campaign and other measures such as universal admission screening. Surgical site infection (SSI) is probably the most preventable HCAI, yet due to the inconsistent implementation of level 1A evidence-based interventions, the UK and US have shown disappointing failures to reduce SSI. The reason for this lack of progress in SSI likely reflects poor compliance with guidelines and checklists.

KW - Healthcare associated infection

UR - http://ewma.org/what-we-do/ewma-journal/previous-issues/

M3 - Article

VL - 14

SP - 35

EP - 37

JO - EWMA Journal

JF - EWMA Journal

SN - 1609-2759

IS - 2

ER -