Hold the fold: how delayed folding aids protein secretion

Nicholas McCaul; Ineke Braakman

doi:10.15252/embj.2022112787

Hold the fold: how delayed folding aids protein secretion

Nicholas McCaul, Ineke Braakman

Research output: Contribution to journal › Review article

2 Citations (Scopus)

Abstract

In bacteria, N-terminal signal peptides mark proteins for transport across the plasma membrane. A recent study by Smets et al (2022) followed the folding of a pair of structural twins to shed light on how evolution has optimised the secretory process.

Original language	English
Article number	e112787
Number of pages	3
Journal	EMBO Journal
Volume	41
Issue number	23
Early online date	31 Oct 2022
DOIs	https://doi.org/10.15252/embj.2022112787
Publication status	Published - 1 Dec 2022

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title = "Hold the fold: how delayed folding aids protein secretion",

abstract = "In bacteria, N-terminal signal peptides mark proteins for transport across the plasma membrane. A recent study by Smets et al (2022) followed the folding of a pair of structural twins to shed light on how evolution has optimised the secretory process.",

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AU - Braakman, Ineke

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AB - In bacteria, N-terminal signal peptides mark proteins for transport across the plasma membrane. A recent study by Smets et al (2022) followed the folding of a pair of structural twins to shed light on how evolution has optimised the secretory process.

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KW - bacteria

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DO - 10.15252/embj.2022112787

M3 - Review article

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Hold the fold: how delayed folding aids protein secretion

Abstract

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