Abstract
Activated γ-lactams, which are derivatives of succinimide, phthalimide and isatin with suitable elements of molecular recognition, have been synthesised as mimics of the β-lactam antibiotics and their chemical and biological reactivity determined.
| Original language | English |
|---|---|
| Pages (from-to) | 125-144 |
| Number of pages | 20 |
| Journal | Arkivoc |
| Volume | 2002 |
| Issue number | 6 |
| Early online date | 23 Aug 2002 |
| Publication status | Published - Dec 2002 |
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Imide and isatin derivatives as γ-lactam mimics of β-lactamantibiotics. / Hadfield, Peter S.; Casey, Lorraine A.; Galt, Ronald H.B.; Vilanova, Bartholomew; Page, Michael I.
In: Arkivoc, Vol. 2002, No. 6, 12.2002, p. 125-144.Research output: Contribution to journal › Article
TY - JOUR
T1 - Imide and isatin derivatives as γ-lactam mimics of β-lactamantibiotics
AU - Hadfield, Peter S.
AU - Casey, Lorraine A.
AU - Galt, Ronald H.B.
AU - Vilanova, Bartholomew
AU - Page, Michael I.
PY - 2002/12
Y1 - 2002/12
N2 - Activated γ-lactams, which are derivatives of succinimide, phthalimide and isatin with suitable elements of molecular recognition, have been synthesised as mimics of the β-lactam antibiotics and their chemical and biological reactivity determined.
AB - Activated γ-lactams, which are derivatives of succinimide, phthalimide and isatin with suitable elements of molecular recognition, have been synthesised as mimics of the β-lactam antibiotics and their chemical and biological reactivity determined.
KW - β-lactamase
KW - γ-lactams
KW - Antibacterials
KW - Hydrolysis
KW - Imides
KW - Isatins
UR - http://www.scopus.com/inward/record.url?scp=3242790999&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:3242790999
VL - 2002
SP - 125
EP - 144
JO - Arkivoc
JF - Arkivoc
SN - 1551-7004
IS - 6
ER -