Imide and isatin derivatives as γ-lactam mimics of β-lactamantibiotics

Peter S. Hadfield, Lorraine A. Casey, Ronald H.B. Galt, Bartholomew Vilanova, Michael I. Page

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Activated γ-lactams, which are derivatives of succinimide, phthalimide and isatin with suitable elements of molecular recognition, have been synthesised as mimics of the β-lactam antibiotics and their chemical and biological reactivity determined.

LanguageEnglish
Pages125-144
Number of pages20
JournalArkivoc
Volume2002
Issue number6
Early online date23 Aug 2002
Publication statusPublished - Dec 2002

Fingerprint

Isatin
Imides
Lactams
Molecular recognition
beta-Lactams
Anti-Bacterial Agents
Derivatives
phthalimide
succinimide

Cite this

Hadfield, P. S., Casey, L. A., Galt, R. H. B., Vilanova, B., & Page, M. I. (2002). Imide and isatin derivatives as γ-lactam mimics of β-lactamantibiotics. Arkivoc, 2002(6), 125-144.
Hadfield, Peter S. ; Casey, Lorraine A. ; Galt, Ronald H.B. ; Vilanova, Bartholomew ; Page, Michael I. / Imide and isatin derivatives as γ-lactam mimics of β-lactamantibiotics. In: Arkivoc. 2002 ; Vol. 2002, No. 6. pp. 125-144.
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Hadfield, PS, Casey, LA, Galt, RHB, Vilanova, B & Page, MI 2002, 'Imide and isatin derivatives as γ-lactam mimics of β-lactamantibiotics', Arkivoc, vol. 2002, no. 6, pp. 125-144.

Imide and isatin derivatives as γ-lactam mimics of β-lactamantibiotics. / Hadfield, Peter S.; Casey, Lorraine A.; Galt, Ronald H.B.; Vilanova, Bartholomew; Page, Michael I.

In: Arkivoc, Vol. 2002, No. 6, 12.2002, p. 125-144.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Imide and isatin derivatives as γ-lactam mimics of β-lactamantibiotics

AU - Hadfield, Peter S.

AU - Casey, Lorraine A.

AU - Galt, Ronald H.B.

AU - Vilanova, Bartholomew

AU - Page, Michael I.

PY - 2002/12

Y1 - 2002/12

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AB - Activated γ-lactams, which are derivatives of succinimide, phthalimide and isatin with suitable elements of molecular recognition, have been synthesised as mimics of the β-lactam antibiotics and their chemical and biological reactivity determined.

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KW - γ-lactams

KW - Antibacterials

KW - Hydrolysis

KW - Imides

KW - Isatins

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M3 - Article

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JF - Arkivoc

SN - 1551-7004

IS - 6

ER -

Hadfield PS, Casey LA, Galt RHB, Vilanova B, Page MI. Imide and isatin derivatives as γ-lactam mimics of β-lactamantibiotics. Arkivoc. 2002 Dec;2002(6):125-144.