Incidence and risk of diabetes mellitus associated with depressive symptoms in adults: Evidence from longitudinal studies

Syed Shahzad Hasan, Alexandra M. Clavarino, Abdullah A. Mamun, Therese Kairuz

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Aims We estimated the incidence and risk of diabetes associated with depressive symptoms using data from longitudinal studies. Materials and methods Databases were systematically searched for relevant studies. Incidence of diabetes is presented as cumulative incident proportion (CIP). Pooled effect sizes were calculated using random-effects model. The data were reconstructed to compute relative risk (RR). Results The 16 studies selected for review generated 16 datasets of which 8 studies reporting binary estimates (RR) and 8 studies reporting time-to-event estimates (hazard ratio (HR)). Both RR and HR were significant at 1.67 (95% CI: 1.30-2.15) and 1.45 (95% CI: 1.12-1.87) for incident diabetes associated with depressive symptoms. Conclusion Our observations revealed greater cumulative incidence of diabetes in depressed than in non depressed groups. Depression should be included among risk factors that required regular screening for diabetes.

LanguageEnglish
Pages82-87
Number of pages6
JournalDiabetes and Metabolic Syndrome: Clinical Research and Reviews
Volume8
Issue number2
DOIs
Publication statusPublished - Apr 2014
Externally publishedYes

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Longitudinal Studies
Diabetes Mellitus
Depression
Incidence
Odds Ratio
Databases

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title = "Incidence and risk of diabetes mellitus associated with depressive symptoms in adults: Evidence from longitudinal studies",
abstract = "Aims We estimated the incidence and risk of diabetes associated with depressive symptoms using data from longitudinal studies. Materials and methods Databases were systematically searched for relevant studies. Incidence of diabetes is presented as cumulative incident proportion (CIP). Pooled effect sizes were calculated using random-effects model. The data were reconstructed to compute relative risk (RR). Results The 16 studies selected for review generated 16 datasets of which 8 studies reporting binary estimates (RR) and 8 studies reporting time-to-event estimates (hazard ratio (HR)). Both RR and HR were significant at 1.67 (95{\%} CI: 1.30-2.15) and 1.45 (95{\%} CI: 1.12-1.87) for incident diabetes associated with depressive symptoms. Conclusion Our observations revealed greater cumulative incidence of diabetes in depressed than in non depressed groups. Depression should be included among risk factors that required regular screening for diabetes.",
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Incidence and risk of diabetes mellitus associated with depressive symptoms in adults : Evidence from longitudinal studies. / Hasan, Syed Shahzad; Clavarino, Alexandra M.; Mamun, Abdullah A.; Kairuz, Therese.

In: Diabetes and Metabolic Syndrome: Clinical Research and Reviews, Vol. 8, No. 2, 04.2014, p. 82-87.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Incidence and risk of diabetes mellitus associated with depressive symptoms in adults

T2 - Diabetes and Metabolic Syndrome: Clinical Research and Reviews

AU - Hasan, Syed Shahzad

AU - Clavarino, Alexandra M.

AU - Mamun, Abdullah A.

AU - Kairuz, Therese

PY - 2014/4

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AB - Aims We estimated the incidence and risk of diabetes associated with depressive symptoms using data from longitudinal studies. Materials and methods Databases were systematically searched for relevant studies. Incidence of diabetes is presented as cumulative incident proportion (CIP). Pooled effect sizes were calculated using random-effects model. The data were reconstructed to compute relative risk (RR). Results The 16 studies selected for review generated 16 datasets of which 8 studies reporting binary estimates (RR) and 8 studies reporting time-to-event estimates (hazard ratio (HR)). Both RR and HR were significant at 1.67 (95% CI: 1.30-2.15) and 1.45 (95% CI: 1.12-1.87) for incident diabetes associated with depressive symptoms. Conclusion Our observations revealed greater cumulative incidence of diabetes in depressed than in non depressed groups. Depression should be included among risk factors that required regular screening for diabetes.

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