Intramolecular 1,3-dipolar cycloaddition as a route to triazolobenzodiazepines and pyrrolobenzodiazepines

Keyphrases

• 1,3-dipolar Cycloaddition 100%
• Pyrrolobenzodiazepine 100%
• Alkynes 100%
• Triazolobenzodiazepines 100%
• Amino Acids 50%
• Aldehydes 50%
• 1,4-Benzodiazepine 50%
• Benzothiadiazepine 50%
• Azides 50%
• Medicinal Chemistry 50%
• Azido 50%
• Transient Intermediates 50%
• Bestmann-Ohira Reagent 50%
• Privileged Structures 50%

Chemistry

• 1,3-cycloaddition 100%
• Pyrrolobenzodiazepine 100%
• Alkyne 100%
• Triazolobenzodiazepine 100%
• Aldehyde 50%
• Chemistry 50%
• Azide 50%
• 1,4-benzodiazepine 50%
• Amino Acid 50%