Investigation of polarization-sensitive optical coherence tomography towards the study of microstructure of articular cartilage

Deepa Kasaragod; Zenghai Lu; Christine Le Maitre; J. Mark Wilkinson; Stephen Matcher

doi:10.1117/12.2006831

Investigation of polarization-sensitive optical coherence tomography towards the study of microstructure of articular cartilage

Deepa Kasaragod, Zenghai Lu, Christine Le Maitre, J. Mark Wilkinson, Stephen Matcher

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

This paper highlights the extended Jones matrix calculus based multi-angle study carried out to understand the depth dependent structural orientation of the collagen fibers in articular cartilage using polarization-sensitive optical coherence tomography (PS-OCT). A 3D lamellar model for the collagen fiber orientation, with a quadratic profile for the arching of the collagen fibers in transitional zone which points towards an ordered arrangement of fibers in that zone is the basis of the organization architecture of collagen fibers in articular cartilage. Experimental data for both ex-vivo bovine fetlock and human patellar cartilage samples are compared with theoretical predictions, with a good quantitative agreement for bovine and a reasonable qualitative agreement for human articular cartilage samples being obtained.

Original language	English
Title of host publication	Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII
Editors	James G. Fujimoto, Joseph A. Izatt, Valery V. Tuchin
Publisher	SPIE
Number of pages	6
Volume	8571
ISBN (Print)	9780819493408
DOIs	https://doi.org/10.1117/12.2006831
Publication status	Published - 20 Mar 2013
Externally published	Yes
Event	Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII - San Francisco, United States Duration: 2 Feb 2013 → 7 Feb 2013 Conference number: 17

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	8571
ISSN (Print)	1605-7422

Conference

Conference	Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII
Country/Territory	United States
City	San Francisco
Period	2/02/13 → 7/02/13

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1117/12.2006831Licence: Unspecified

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Kasaragod, D., Lu, Z., Le Maitre, C., Wilkinson, J. M., & Matcher, S. (2013). Investigation of polarization-sensitive optical coherence tomography towards the study of microstructure of articular cartilage. In J. G. Fujimoto, J. A. Izatt, & V. V. Tuchin (Eds.), Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII (Vol. 8571). Article 85712K (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8571). SPIE. https://doi.org/10.1117/12.2006831

Kasaragod, Deepa ; Lu, Zenghai ; Le Maitre, Christine et al. / Investigation of polarization-sensitive optical coherence tomography towards the study of microstructure of articular cartilage. Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII. editor / James G. Fujimoto ; Joseph A. Izatt ; Valery V. Tuchin. Vol. 8571 SPIE, 2013. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).

@inproceedings{30952cf234cd4557a43994ab852c6a74,

title = "Investigation of polarization-sensitive optical coherence tomography towards the study of microstructure of articular cartilage",

abstract = "This paper highlights the extended Jones matrix calculus based multi-angle study carried out to understand the depth dependent structural orientation of the collagen fibers in articular cartilage using polarization-sensitive optical coherence tomography (PS-OCT). A 3D lamellar model for the collagen fiber orientation, with a quadratic profile for the arching of the collagen fibers in transitional zone which points towards an ordered arrangement of fibers in that zone is the basis of the organization architecture of collagen fibers in articular cartilage. Experimental data for both ex-vivo bovine fetlock and human patellar cartilage samples are compared with theoretical predictions, with a good quantitative agreement for bovine and a reasonable qualitative agreement for human articular cartilage samples being obtained.",

keywords = "articular cartilage, birefringence, collagen, extended Jones matrix calculus, osteoarthritis, polarization-sensitive OCT, Cartilage, Optical coherence tomography, Optical fibers, Tissues, Natural surfaces, Bone, Data modeling, Birefringence, Tissue optics",

author = "Deepa Kasaragod and Zenghai Lu and \{Le Maitre\}, Christine and Wilkinson, \{J. Mark\} and Stephen Matcher",

year = "2013",

month = mar,

day = "20",

doi = "10.1117/12.2006831",

language = "English",

isbn = "9780819493408",

volume = "8571",

series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

publisher = "SPIE",

editor = "Fujimoto, \{James G.\} and Izatt, \{Joseph A.\} and Tuchin, \{Valery V.\}",

booktitle = "Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII",

address = "United States",

note = "Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII ; Conference date: 02-02-2013 Through 07-02-2013",

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Kasaragod, D, Lu, Z, Le Maitre, C, Wilkinson, JM & Matcher, S 2013, Investigation of polarization-sensitive optical coherence tomography towards the study of microstructure of articular cartilage. in JG Fujimoto, JA Izatt & VV Tuchin (eds), Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII. vol. 8571, 85712K, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 8571, SPIE, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII, San Francisco, California, United States, 2/02/13. https://doi.org/10.1117/12.2006831

Investigation of polarization-sensitive optical coherence tomography towards the study of microstructure of articular cartilage. / Kasaragod, Deepa; Lu, Zenghai; Le Maitre, Christine et al.
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII. ed. / James G. Fujimoto; Joseph A. Izatt; Valery V. Tuchin. Vol. 8571 SPIE, 2013. 85712K (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8571).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Investigation of polarization-sensitive optical coherence tomography towards the study of microstructure of articular cartilage

AU - Kasaragod, Deepa

AU - Lu, Zenghai

AU - Le Maitre, Christine

AU - Wilkinson, J. Mark

AU - Matcher, Stephen

N1 - Conference code: 17

PY - 2013/3/20

Y1 - 2013/3/20

N2 - This paper highlights the extended Jones matrix calculus based multi-angle study carried out to understand the depth dependent structural orientation of the collagen fibers in articular cartilage using polarization-sensitive optical coherence tomography (PS-OCT). A 3D lamellar model for the collagen fiber orientation, with a quadratic profile for the arching of the collagen fibers in transitional zone which points towards an ordered arrangement of fibers in that zone is the basis of the organization architecture of collagen fibers in articular cartilage. Experimental data for both ex-vivo bovine fetlock and human patellar cartilage samples are compared with theoretical predictions, with a good quantitative agreement for bovine and a reasonable qualitative agreement for human articular cartilage samples being obtained.

AB - This paper highlights the extended Jones matrix calculus based multi-angle study carried out to understand the depth dependent structural orientation of the collagen fibers in articular cartilage using polarization-sensitive optical coherence tomography (PS-OCT). A 3D lamellar model for the collagen fiber orientation, with a quadratic profile for the arching of the collagen fibers in transitional zone which points towards an ordered arrangement of fibers in that zone is the basis of the organization architecture of collagen fibers in articular cartilage. Experimental data for both ex-vivo bovine fetlock and human patellar cartilage samples are compared with theoretical predictions, with a good quantitative agreement for bovine and a reasonable qualitative agreement for human articular cartilage samples being obtained.

KW - articular cartilage

KW - birefringence

KW - collagen

KW - extended Jones matrix calculus

KW - osteoarthritis

KW - polarization-sensitive OCT

KW - Cartilage

KW - Optical coherence tomography

KW - Optical fibers

KW - Tissues

KW - Natural surfaces

KW - Bone

KW - Data modeling

KW - Birefringence

KW - Tissue optics

UR - https://www.scopus.com/pages/publications/84877864348

U2 - 10.1117/12.2006831

DO - 10.1117/12.2006831

M3 - Conference contribution

AN - SCOPUS:84877864348

SN - 9780819493408

VL - 8571

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII

A2 - Fujimoto, James G.

A2 - Izatt, Joseph A.

A2 - Tuchin, Valery V.

PB - SPIE

T2 - Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII

Y2 - 2 February 2013 through 7 February 2013

ER -

Kasaragod D, Lu Z, Le Maitre C, Wilkinson JM, Matcher S. Investigation of polarization-sensitive optical coherence tomography towards the study of microstructure of articular cartilage. In Fujimoto JG, Izatt JA, Tuchin VV, editors, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII. Vol. 8571. SPIE. 2013. 85712K. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.2006831

Investigation of polarization-sensitive optical coherence tomography towards the study of microstructure of articular cartilage

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