Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones: synthesis of 2-oxazolines

Somaia Kamouka; Wesley J Moran

doi:10.3762/bjoc.13.177

Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones: synthesis of 2-oxazolines

Somaia Kamouka, Wesley J Moran

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Two complementary iodoarene-catalyzed methods for the preparation of 2-oxazolines are presented. The first involves the cyclization of N-propargylamides and the second involves the cyclization of β-amidoketones. These are proposed to proceed through different mechanisms and have different substrate scopes.

Original language	English
Pages (from-to)	1823-1827
Number of pages	5
Journal	Beilstein Journal of Organic Chemistry
Volume	13
DOIs	https://doi.org/10.3762/bjoc.13.177
Publication status	Published - 31 Aug 2017

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10.3762/bjoc.13.177Licence: CC BY

http://eprints.hud.ac.uk/id/eprint/33075/Licence: CC BY
http://www.beilstein-journals.org/bjoc/content/13/1/177Licence: CC BY

Cite this

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title = "Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones: synthesis of 2-oxazolines",

abstract = "Two complementary iodoarene-catalyzed methods for the preparation of 2-oxazolines are presented. The first involves the cyclization of N-propargylamides and the second involves the cyclization of β-amidoketones. These are proposed to proceed through different mechanisms and have different substrate scopes.",

keywords = "amides, catalysis, cyclization, hypervalent iodine, isoxazolines",

author = "Somaia Kamouka and Moran, {Wesley J}",

year = "2017",

month = aug,

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doi = "10.3762/bjoc.13.177",

language = "English",

volume = "13",

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journal = "Beilstein Journal of Organic Chemistry",

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T1 - Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones

T2 - synthesis of 2-oxazolines

AU - Kamouka, Somaia

AU - Moran, Wesley J

PY - 2017/8/31

Y1 - 2017/8/31

N2 - Two complementary iodoarene-catalyzed methods for the preparation of 2-oxazolines are presented. The first involves the cyclization of N-propargylamides and the second involves the cyclization of β-amidoketones. These are proposed to proceed through different mechanisms and have different substrate scopes.

AB - Two complementary iodoarene-catalyzed methods for the preparation of 2-oxazolines are presented. The first involves the cyclization of N-propargylamides and the second involves the cyclization of β-amidoketones. These are proposed to proceed through different mechanisms and have different substrate scopes.

KW - amides

KW - catalysis

KW - cyclization

KW - hypervalent iodine

KW - isoxazolines

U2 - 10.3762/bjoc.13.177

DO - 10.3762/bjoc.13.177

M3 - Article

VL - 13

SP - 1823

EP - 1827

JO - Beilstein Journal of Organic Chemistry

JF - Beilstein Journal of Organic Chemistry

SN - 1860-5397

ER -

Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones: synthesis of 2-oxazolines

Abstract

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