Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones

synthesis of 2-oxazolines

Somaia Kamouka, Wesley J Moran

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Two complementary iodoarene-catalyzed methods for the preparation of 2-oxazolines are presented. The first involves the cyclization of N-propargylamides and the second involves the cyclization of β-amidoketones. These are proposed to proceed through different mechanisms and have different substrate scopes.
Original languageEnglish
Pages (from-to)1823-1827
Number of pages5
JournalBeilstein Journal of Organic Chemistry
Volume13
DOIs
Publication statusPublished - 31 Aug 2017

Fingerprint

Cyclization
Substrates

Cite this

@article{ee0e0746adcb4f8ab5aaf311efd86319,
title = "Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones: synthesis of 2-oxazolines",
abstract = "Two complementary iodoarene-catalyzed methods for the preparation of 2-oxazolines are presented. The first involves the cyclization of N-propargylamides and the second involves the cyclization of β-amidoketones. These are proposed to proceed through different mechanisms and have different substrate scopes.",
keywords = "amides, catalysis, cyclization, hypervalent iodine, isoxazolines",
author = "Somaia Kamouka and Moran, {Wesley J}",
year = "2017",
month = "8",
day = "31",
doi = "10.3762/bjoc.13.177",
language = "English",
volume = "13",
pages = "1823--1827",
journal = "Beilstein Journal of Organic Chemistry",
issn = "1860-5397",
publisher = "Beilstein-Institut Zur Forderung der Chemischen Wissenschaften",

}

Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones : synthesis of 2-oxazolines. / Kamouka, Somaia; Moran, Wesley J.

In: Beilstein Journal of Organic Chemistry, Vol. 13, 31.08.2017, p. 1823-1827.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Iodoarene-catalyzed cyclizations of N-propargylamides and β-amidoketones

T2 - synthesis of 2-oxazolines

AU - Kamouka, Somaia

AU - Moran, Wesley J

PY - 2017/8/31

Y1 - 2017/8/31

N2 - Two complementary iodoarene-catalyzed methods for the preparation of 2-oxazolines are presented. The first involves the cyclization of N-propargylamides and the second involves the cyclization of β-amidoketones. These are proposed to proceed through different mechanisms and have different substrate scopes.

AB - Two complementary iodoarene-catalyzed methods for the preparation of 2-oxazolines are presented. The first involves the cyclization of N-propargylamides and the second involves the cyclization of β-amidoketones. These are proposed to proceed through different mechanisms and have different substrate scopes.

KW - amides

KW - catalysis

KW - cyclization

KW - hypervalent iodine

KW - isoxazolines

U2 - 10.3762/bjoc.13.177

DO - 10.3762/bjoc.13.177

M3 - Article

VL - 13

SP - 1823

EP - 1827

JO - Beilstein Journal of Organic Chemistry

JF - Beilstein Journal of Organic Chemistry

SN - 1860-5397

ER -