Magnetic field effects in flavoproteins and related systems

Emrys W. Evans, Charlotte A. Dodson, Kiminori Maeda, Till Biskup, C. J. Wedge, Christiane R. Timme

Research output: Contribution to journalReview article

24 Citations (Scopus)

Abstract

Within the framework of the radical pair mechanism, magnetic fields may alter the rate and yields of chemical reactions involving spin-correlated radical pairs as intermediates. Such effects have been studied in detail in a variety of chemical systems both experimentally and theoretically. In recent years, there has been growing interest in whether such magnetic field effects (MFEs) also occur in biological systems, a question driven most notably by the increasing body of evidence for the involvement of such effects in the magnetic compass sense of animals. The blue-light photoreceptor cryptochrome is placed at the centre of this debate and photo excitation of its bound flavin cofactor has indeed been shown to result in the formation of radical pairs. Here, we review studies of MFEs on free flavins in model systems as well as in blue-light photoreceptor proteins and discuss the properties that are crucial in determining the magnetosensitivity of these systems.

Original languageEnglish
Number of pages17
JournalInterface Focus
Volume3
Issue number5
Early online date23 Aug 2013
DOIs
Publication statusPublished - 6 Oct 2013
Externally publishedYes

Fingerprint

Magnetic field effects
Flavoproteins
Magnetic Fields
Cryptochromes
Flavins
Photoexcitation
Biological systems
Light
Chemical reactions
Animals
Magnetic fields
Proteins
4,6-dinitro-o-cresol

Cite this

Evans, E. W., Dodson, C. A., Maeda, K., Biskup, T., Wedge, C. J., & Timme, C. R. (2013). Magnetic field effects in flavoproteins and related systems. Interface Focus, 3(5). https://doi.org/10.1098/rsfs.2013.0037
Evans, Emrys W. ; Dodson, Charlotte A. ; Maeda, Kiminori ; Biskup, Till ; Wedge, C. J. ; Timme, Christiane R. / Magnetic field effects in flavoproteins and related systems. In: Interface Focus. 2013 ; Vol. 3, No. 5.
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Evans, EW, Dodson, CA, Maeda, K, Biskup, T, Wedge, CJ & Timme, CR 2013, 'Magnetic field effects in flavoproteins and related systems', Interface Focus, vol. 3, no. 5. https://doi.org/10.1098/rsfs.2013.0037

Magnetic field effects in flavoproteins and related systems. / Evans, Emrys W.; Dodson, Charlotte A.; Maeda, Kiminori; Biskup, Till; Wedge, C. J.; Timme, Christiane R.

In: Interface Focus, Vol. 3, No. 5, 06.10.2013.

Research output: Contribution to journalReview article

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