Male genes: X-pelled or X-cluded?

David W. Rogers, Martin Carr, Andrew Pomiankowski

Research output: Contribution to journalReview articlepeer-review

23 Citations (Scopus)


Two recent studies by Parisi et al. and Ranz et al., catalogue sex differences in gene expression across the whole genome of the fruit fly Drosophila melanogaster. Both report striking associations of sex-biased gene expression with the X chromosome. Genes with male-biased expression are depauperate on the X chromosome, whereas genes with female-biased expression show weaker evidence of being in excess. A number of evolutionary hypotheses for the expulsion or exclusion of male-biased genes from the X chromosome have been suggested. None is entirely consistent with the available evidence.

Original languageEnglish
Pages (from-to)739-741
Number of pages3
Issue number8
Early online date18 Jul 2003
Publication statusPublished - 1 Aug 2003
Externally publishedYes


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