Mapping human dispersals into the Horn of Africa from Arabian Ice Age refugia using mitogenomes

Francesca Gandini, Alessandro Achilli, Maria Pala, Martin Bodner, Stefania Brandini, Gabriela Huber, Balazs Egyed, Luca Ferretti, Alberto Gómez-Carballa, Antonio Salas, Rosaria Scozzari, Fulvio Cruciani, Alfredo Coppa, Walther Parson, Ornella Semino, Pedro Soares, Antonio Torroni, Martin B. Richards, Anna Olivieri

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Rare mitochondrial lineages with relict distributions can sometimes be disproportionately informative about deep events in human prehistory. We have studied one such lineage, haplogroup R0a, which uniquely is most frequent in Arabia and the Horn of Africa, but is distributed much more widely, from Europe to India. We conclude that: (1) the lineage ancestral to R0a is more ancient than previously thought, with a relict distribution across the Mediterranean/Southwest Asia; (2) R0a has a much deeper presence in Arabia than previously thought, highlighting the role of at least one Pleistocene glacial refugium, perhaps on the Red Sea plains; (3) the main episode of dispersal into Eastern Africa, at least concerning maternal lineages, was at the end of the Late Glacial, due to major expansions from one or more refugia in Arabia; (4) there was likely a minor Late Glacial/early postglacial dispersal from Arabia through the Levant and into Europe, possibly alongside other lineages from a Levantine refugium; and (5) the presence of R0a in Southwest Arabia in the Holocene at the nexus of a trading network that developed after ∼3 ka between Africa and the Indian Ocean led to some gene flow even further afield, into Iran, Pakistan and India.

LanguageEnglish
Article number25472
JournalScientific Reports
Volume6
DOIs
Publication statusPublished - 5 May 2016

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refugium
Pleistocene
late glacial
Postglacial
gene flow
Holocene
Africa
distribution
Europe

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Gandini, Francesca ; Achilli, Alessandro ; Pala, Maria ; Bodner, Martin ; Brandini, Stefania ; Huber, Gabriela ; Egyed, Balazs ; Ferretti, Luca ; Gómez-Carballa, Alberto ; Salas, Antonio ; Scozzari, Rosaria ; Cruciani, Fulvio ; Coppa, Alfredo ; Parson, Walther ; Semino, Ornella ; Soares, Pedro ; Torroni, Antonio ; Richards, Martin B. ; Olivieri, Anna. / Mapping human dispersals into the Horn of Africa from Arabian Ice Age refugia using mitogenomes. In: Scientific Reports. 2016 ; Vol. 6.
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abstract = "Rare mitochondrial lineages with relict distributions can sometimes be disproportionately informative about deep events in human prehistory. We have studied one such lineage, haplogroup R0a, which uniquely is most frequent in Arabia and the Horn of Africa, but is distributed much more widely, from Europe to India. We conclude that: (1) the lineage ancestral to R0a is more ancient than previously thought, with a relict distribution across the Mediterranean/Southwest Asia; (2) R0a has a much deeper presence in Arabia than previously thought, highlighting the role of at least one Pleistocene glacial refugium, perhaps on the Red Sea plains; (3) the main episode of dispersal into Eastern Africa, at least concerning maternal lineages, was at the end of the Late Glacial, due to major expansions from one or more refugia in Arabia; (4) there was likely a minor Late Glacial/early postglacial dispersal from Arabia through the Levant and into Europe, possibly alongside other lineages from a Levantine refugium; and (5) the presence of R0a in Southwest Arabia in the Holocene at the nexus of a trading network that developed after ∼3 ka between Africa and the Indian Ocean led to some gene flow even further afield, into Iran, Pakistan and India.",
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Gandini, F, Achilli, A, Pala, M, Bodner, M, Brandini, S, Huber, G, Egyed, B, Ferretti, L, Gómez-Carballa, A, Salas, A, Scozzari, R, Cruciani, F, Coppa, A, Parson, W, Semino, O, Soares, P, Torroni, A, Richards, MB & Olivieri, A 2016, 'Mapping human dispersals into the Horn of Africa from Arabian Ice Age refugia using mitogenomes', Scientific Reports, vol. 6, 25472. https://doi.org/10.1038/srep25472

Mapping human dispersals into the Horn of Africa from Arabian Ice Age refugia using mitogenomes. / Gandini, Francesca; Achilli, Alessandro; Pala, Maria; Bodner, Martin; Brandini, Stefania; Huber, Gabriela; Egyed, Balazs; Ferretti, Luca; Gómez-Carballa, Alberto; Salas, Antonio; Scozzari, Rosaria; Cruciani, Fulvio; Coppa, Alfredo; Parson, Walther; Semino, Ornella; Soares, Pedro; Torroni, Antonio; Richards, Martin B.; Olivieri, Anna.

In: Scientific Reports, Vol. 6, 25472, 05.05.2016.

Research output: Contribution to journalArticle

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AU - Gandini, Francesca

AU - Achilli, Alessandro

AU - Pala, Maria

AU - Bodner, Martin

AU - Brandini, Stefania

AU - Huber, Gabriela

AU - Egyed, Balazs

AU - Ferretti, Luca

AU - Gómez-Carballa, Alberto

AU - Salas, Antonio

AU - Scozzari, Rosaria

AU - Cruciani, Fulvio

AU - Coppa, Alfredo

AU - Parson, Walther

AU - Semino, Ornella

AU - Soares, Pedro

AU - Torroni, Antonio

AU - Richards, Martin B.

AU - Olivieri, Anna

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