Measuring three-dimensional strain distribution in tendon

G. Khodabakhshi, D. Walker, A. Scutt, L. Way, R. M. Cowie, D. R. Hose

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Tendons are tough fibrous tissues that facilitate skeletal movement by transferring muscular force to bone. Studies into the effects of mechanical stress on tendons have shown that these can either accelerate healing or cause tendon injuries depending on the load applied. It is known that local strain magnitude and direction play an important role in tendon remodelling and also failure, and different techniques to study strain distribution have been proposed. Image registration and processing techniques are among the recently employed methods. In this study, a novel three-dimensional image processing technique using the Sheffield Image Registration Toolkit is introduced to study local strain and displacement distribution in tendon. The results show that the local normal strain values in the loading axis are smaller than the global applied load, and fibre sliding was detected as a dominant mechanism for transferring the applied load within tendon. However, results from different samples suggest three distinct modes of deformation during loading, as some show only parallel sliding of fibres in respect to the loading axis, whereas others are twisted or deflected in directions transverse to the loading axis. The proposed 3D image registration method is essential for analysing this out-of-plane movement, which cannot be detected using a standard 2D method.

Original languageEnglish
Pages (from-to)195-205
Number of pages11
JournalJournal of Microscopy
Volume249
Issue number3
Early online date16 Jan 2013
DOIs
Publication statusPublished - Mar 2013
Externally publishedYes

Fingerprint

Tendons
Tendon Injuries
Mechanical Stress
Three-Dimensional Imaging
Reference Values
Bone and Bones
Direction compound

Cite this

Khodabakhshi, G., Walker, D., Scutt, A., Way, L., Cowie, R. M., & Hose, D. R. (2013). Measuring three-dimensional strain distribution in tendon. Journal of Microscopy, 249(3), 195-205. https://doi.org/10.1111/jmi.12009
Khodabakhshi, G. ; Walker, D. ; Scutt, A. ; Way, L. ; Cowie, R. M. ; Hose, D. R. / Measuring three-dimensional strain distribution in tendon. In: Journal of Microscopy. 2013 ; Vol. 249, No. 3. pp. 195-205.
@article{e1645cfe4d8f47a59ade717ef1067493,
title = "Measuring three-dimensional strain distribution in tendon",
abstract = "Tendons are tough fibrous tissues that facilitate skeletal movement by transferring muscular force to bone. Studies into the effects of mechanical stress on tendons have shown that these can either accelerate healing or cause tendon injuries depending on the load applied. It is known that local strain magnitude and direction play an important role in tendon remodelling and also failure, and different techniques to study strain distribution have been proposed. Image registration and processing techniques are among the recently employed methods. In this study, a novel three-dimensional image processing technique using the Sheffield Image Registration Toolkit is introduced to study local strain and displacement distribution in tendon. The results show that the local normal strain values in the loading axis are smaller than the global applied load, and fibre sliding was detected as a dominant mechanism for transferring the applied load within tendon. However, results from different samples suggest three distinct modes of deformation during loading, as some show only parallel sliding of fibres in respect to the loading axis, whereas others are twisted or deflected in directions transverse to the loading axis. The proposed 3D image registration method is essential for analysing this out-of-plane movement, which cannot be detected using a standard 2D method.",
keywords = "Confocal microscopy, Image processing, Strain measurement, Tendon",
author = "G. Khodabakhshi and D. Walker and A. Scutt and L. Way and Cowie, {R. M.} and Hose, {D. R.}",
year = "2013",
month = "3",
doi = "10.1111/jmi.12009",
language = "English",
volume = "249",
pages = "195--205",
journal = "Journal of Microscopy",
issn = "0022-2720",
publisher = "Wiley-Blackwell",
number = "3",

}

Khodabakhshi, G, Walker, D, Scutt, A, Way, L, Cowie, RM & Hose, DR 2013, 'Measuring three-dimensional strain distribution in tendon', Journal of Microscopy, vol. 249, no. 3, pp. 195-205. https://doi.org/10.1111/jmi.12009

Measuring three-dimensional strain distribution in tendon. / Khodabakhshi, G.; Walker, D.; Scutt, A.; Way, L.; Cowie, R. M.; Hose, D. R.

In: Journal of Microscopy, Vol. 249, No. 3, 03.2013, p. 195-205.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Measuring three-dimensional strain distribution in tendon

AU - Khodabakhshi, G.

AU - Walker, D.

AU - Scutt, A.

AU - Way, L.

AU - Cowie, R. M.

AU - Hose, D. R.

PY - 2013/3

Y1 - 2013/3

N2 - Tendons are tough fibrous tissues that facilitate skeletal movement by transferring muscular force to bone. Studies into the effects of mechanical stress on tendons have shown that these can either accelerate healing or cause tendon injuries depending on the load applied. It is known that local strain magnitude and direction play an important role in tendon remodelling and also failure, and different techniques to study strain distribution have been proposed. Image registration and processing techniques are among the recently employed methods. In this study, a novel three-dimensional image processing technique using the Sheffield Image Registration Toolkit is introduced to study local strain and displacement distribution in tendon. The results show that the local normal strain values in the loading axis are smaller than the global applied load, and fibre sliding was detected as a dominant mechanism for transferring the applied load within tendon. However, results from different samples suggest three distinct modes of deformation during loading, as some show only parallel sliding of fibres in respect to the loading axis, whereas others are twisted or deflected in directions transverse to the loading axis. The proposed 3D image registration method is essential for analysing this out-of-plane movement, which cannot be detected using a standard 2D method.

AB - Tendons are tough fibrous tissues that facilitate skeletal movement by transferring muscular force to bone. Studies into the effects of mechanical stress on tendons have shown that these can either accelerate healing or cause tendon injuries depending on the load applied. It is known that local strain magnitude and direction play an important role in tendon remodelling and also failure, and different techniques to study strain distribution have been proposed. Image registration and processing techniques are among the recently employed methods. In this study, a novel three-dimensional image processing technique using the Sheffield Image Registration Toolkit is introduced to study local strain and displacement distribution in tendon. The results show that the local normal strain values in the loading axis are smaller than the global applied load, and fibre sliding was detected as a dominant mechanism for transferring the applied load within tendon. However, results from different samples suggest three distinct modes of deformation during loading, as some show only parallel sliding of fibres in respect to the loading axis, whereas others are twisted or deflected in directions transverse to the loading axis. The proposed 3D image registration method is essential for analysing this out-of-plane movement, which cannot be detected using a standard 2D method.

KW - Confocal microscopy

KW - Image processing

KW - Strain measurement

KW - Tendon

UR - http://www.scopus.com/inward/record.url?scp=84873721813&partnerID=8YFLogxK

UR - http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1365-2818

U2 - 10.1111/jmi.12009

DO - 10.1111/jmi.12009

M3 - Article

VL - 249

SP - 195

EP - 205

JO - Journal of Microscopy

JF - Journal of Microscopy

SN - 0022-2720

IS - 3

ER -

Khodabakhshi G, Walker D, Scutt A, Way L, Cowie RM, Hose DR. Measuring three-dimensional strain distribution in tendon. Journal of Microscopy. 2013 Mar;249(3):195-205. https://doi.org/10.1111/jmi.12009