Methods to Investigate Cell Migration

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Abstract

Cell migration is of great relevance to researchers studying development, wound healing, the immune system and its responses and diseases associated with deregulated cell migration. The study of cell migration has been made possible by the development of a huge variety of experimental set-ups in 2D and 3D focussing on specific aspects of cell migration. In this chapter, some of such specific aspects of cell migration will be discussed and the assays available to investigate the particular features of cell migration. Examples of traditional cell migration assays and most recent developments ranging from wound healing assays to microfluidics studies will be given, followed by commonly used assays in a 3D setting and finally highly specialised intravital in vivo research. The advantages and disadvantages of such assays are highlighted.
Original languageEnglish
Title of host publicationCell Migration in Development, Health and Disease
EditorsAnke Brüning-Richardson, Sabine Knipp
PublisherSpringer, Cham
Pages163-181
Number of pages21
ISBN (Electronic)9783031645327
ISBN (Print)9783031645310
DOIs
Publication statusPublished - 13 Nov 2024

Publication series

NameLearning Materials in Biosciences
PublisherSpringer
ISSN (Print)2509-6125
ISSN (Electronic)2509-6133

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