Multifaceted catalysis approach to nitrile activation: Direct synthesis of halogenated allyl amides from allylic alcohols

Roy P. Lester, Jay J. Dunsford, Jason E. Camp

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Allyl amides were synthesised from the reaction of allyl alcohols and halogenated nitriles using a platinum multifaceted catalysis approach in which both the nucleophilic addition and subsequent [3,3]-sigmatropic rearrangement steps of the process were catalysed by the same complex. Additionally, 1H/13C{1H} NMR and GC studies provided the first insights into the mechanism of this transformation.

Original languageEnglish
Pages (from-to)7472-7476
Number of pages5
JournalOrganic and Biomolecular Chemistry
Volume11
Issue number43
Early online date26 Sep 2013
DOIs
Publication statusPublished - 21 Nov 2013
Externally publishedYes

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