Non-Posturing Macular Hole Surgery with Choice of Tamponade Guided by Hole Base Diameter

Rubina Rahman, M. Anderson, John Stephenson

Research output: Contribution to journalArticlepeer-review


Purpose: Post-operative posturing and choice of intraocular tamponade remain contentious issues in macular hole surgery. We report the results of non-posturing surgery, with choice of tamponade guided by macular hole size.

Methods: In this retrospective consecutive case series, patients underwent non-posturing 23G vitrectomy/phacovitrecomy and ILM peel for idiopathic full-thickness macular holes. Pre-operative hole base diameter was measured using spectral domain OCT. Macular holes with a base diameter (BD) of ≤ 720 �m were tamponaded with 20% SF6 (Sulfur hexafluoride), while larger holes received 20% C2F6 (perfluoro-ethane). The primary hole closure rate and improvement in vision was recorded.

Results: 58 eyes in the SF6 group had a mean macular hole base diameter of 504.8�m (range 95-733�m). 28 eyes in the C2F6 group had a mean macular hole BD of 963.0�m (range 722-1440�m). The primary surgical success rate was 93.5% in the SF6 group and 92.9% in the C2F6 group. Using a Z-test for the equality of two proportions, the proportions of successful procedures in cases with SF6 and C2F6 agents were found to be not significantly different (Z=0.122; p=0.903).

Conclusion: Short acting SF6 gas and medium acting C2F6 gases were effective in closing macular holes with an average preoperative macular hole BD of 504.8 �m and 963.0 �m respectively. Further studies are required to determine, the optimum tamponade guided by preoperative macular hole size.
Original languageEnglish
Article number100107
Pages (from-to)1-4
Number of pages4
JournalJournal of Ophthalmology and Ophthalmic Surgey
Issue number2
Publication statusPublished - 30 Oct 2015


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