On the preparation of ortho-trifluoromethyl phenyl triflate

Duncan Gill, Alison J. Hester, Guy C. Lloyd-Jones

Research output: Contribution to journalReview articlepeer-review

3 Citations (Scopus)


In contrast to an earlier report advocating a copper-mediated trifluoromethylation of ortho-iodophenyl triflate, ortho-trifluoromethyl phenyl triflate may be prepared simply by reacting the corresponding phenol with triflic anhydride in the presence of a nucleophilic catalyst and stoichiometric base.

Original languageEnglish
Pages (from-to)2547-2548
Number of pages2
JournalOrganic and Biomolecular Chemistry
Issue number17
Early online date4 Aug 2004
Publication statusPublished - 7 Sep 2004
Externally publishedYes


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