Abstract
Terahertz (THz) quantum cascade lasers (QCLs) are compact sources of radiation in the 1-5 THz range with significant potential for applications in sensing and imaging. Laser feedback interferometry (LFI) with THz QCLs is a technique utilizing the sensitivity of the QCL to the radiation reflected back into the laser cavity from an external target. We will discuss modelling techniques and explore the applications of LFI in biological tissue imaging and will show that the confocal nature of the QCL in LFI systems, with their innate capacity for depth sectioning, makes them suitable for skin diagnostics with the well-known advantages of more conventional confocal microscopes. A demonstration of discrimination of neoplasia from healthy tissue using a THz, LFI-based system in the context of melanoma is presented using a transgenic mouse model.
Original language | English |
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Title of host publication | Infrared, Millimeter-Wave, and Terahertz Technologies IV |
Editors | Cunlin Zhang, Xi-Cheng Zhang, Masahiko Tani |
Publisher | SPIE |
Number of pages | 12 |
Volume | 10030 |
ISBN (Electronic) | 9781510604803 |
ISBN (Print) | 9781510604797 |
DOIs | |
Publication status | Published - 8 Dec 2016 |
Externally published | Yes |
Event | Infrared, Millimeter-Wave, and Terahertz Technologies IV - Beijing, China Duration: 12 Oct 2016 → 14 Oct 2016 Conference number: 4 |
Publication series
Name | Proceedings of SPIE - The International Society for Optical Engineering |
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Volume | 10030 |
ISSN (Print) | 0277-786X |
ISSN (Electronic) | 1996-756X |
Conference
Conference | Infrared, Millimeter-Wave, and Terahertz Technologies IV |
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Country/Territory | China |
City | Beijing |
Period | 12/10/16 → 14/10/16 |