Osmium(vi) complexes as a new class of potential anti-cancer agents

Wen Xiu Ni, Wai Lun Man, Myra Ting Wai Cheung, Raymond Wai Yin Sun, Yuan Lan Shu, Yun Wah Lam, Chi Ming Che, Tai Chu Lau

Research output: Contribution to journalArticlepeer-review

44 Citations (Scopus)


A nitridoosmium(vi) complex [OsVI(N)(sap)(OH2)Cl] (H2sap = N-salicylidene-2-aminophenol) displays prominent in vitro and in vivo anti-cancer properties, induces S- and G2/M-phase arrest and forms a stable adduct with dianionic 5′-guanosine monophosphate.

Original languageEnglish
Pages (from-to)2140-2142
Number of pages3
JournalChemical Communications
Issue number7
Early online date4 Jan 2011
Publication statusPublished - 21 Feb 2011
Externally publishedYes

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