Pharmacological screening of the methanolic extract of Chenopodium ambrosioides

O. A. Olajide; S. O. Awe; J. M. Makinde

Pharmacological screening of the methanolic extract of Chenopodium ambrosioides

O. A. Olajide, S. O. Awe, J. M. Makinde

University of Ibadan

Research output: Contribution to journal › Short survey › peer-review

20 Citations (Scopus)

Abstract

The methanolic extract of the leaves of C. ambrosioides, administered at 100 and 200 mg/kg i.p., produced an inhibition of the carrageenan-induced rat paw oedema and a reduction in writhings induced by acetic acid in mice. It also exhibited antipyretic effect and induced a strong gastrointestinal propulsive movement in mice. Acute toxicity studies showed no mortality up to 1 g/kg p.o.

Original language	English
Pages (from-to)	529-532
Number of pages	4
Journal	Fitoterapia
Volume	68
Issue number	6
Publication status	Published - 1 Dec 1997
Externally published	Yes

Cite this

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title = "Pharmacological screening of the methanolic extract of Chenopodium ambrosioides",

abstract = "The methanolic extract of the leaves of C. ambrosioides, administered at 100 and 200 mg/kg i.p., produced an inhibition of the carrageenan-induced rat paw oedema and a reduction in writhings induced by acetic acid in mice. It also exhibited antipyretic effect and induced a strong gastrointestinal propulsive movement in mice. Acute toxicity studies showed no mortality up to 1 g/kg p.o.",

keywords = "Anti-inflammatory activity, Antipyretic activity, Chenopodium ambrosioides, Spasmogenic effects",

author = "Olajide, \{O. A.\} and Awe, \{S. O.\} and Makinde, \{J. M.\}",

year = "1997",

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pages = "529--532",

journal = "Fitoterapia",

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T1 - Pharmacological screening of the methanolic extract of Chenopodium ambrosioides

AU - Olajide, O. A.

AU - Awe, S. O.

AU - Makinde, J. M.

PY - 1997/12/1

Y1 - 1997/12/1

N2 - The methanolic extract of the leaves of C. ambrosioides, administered at 100 and 200 mg/kg i.p., produced an inhibition of the carrageenan-induced rat paw oedema and a reduction in writhings induced by acetic acid in mice. It also exhibited antipyretic effect and induced a strong gastrointestinal propulsive movement in mice. Acute toxicity studies showed no mortality up to 1 g/kg p.o.

AB - The methanolic extract of the leaves of C. ambrosioides, administered at 100 and 200 mg/kg i.p., produced an inhibition of the carrageenan-induced rat paw oedema and a reduction in writhings induced by acetic acid in mice. It also exhibited antipyretic effect and induced a strong gastrointestinal propulsive movement in mice. Acute toxicity studies showed no mortality up to 1 g/kg p.o.

KW - Anti-inflammatory activity

KW - Antipyretic activity

KW - Chenopodium ambrosioides

KW - Spasmogenic effects

UR - https://www.scopus.com/pages/publications/0031459015

UR - https://www.sciencedirect.com/journal/fitoterapia

M3 - Short survey

AN - SCOPUS:0031459015

SN - 0367-326X

VL - 68

SP - 529

EP - 532

JO - Fitoterapia

JF - Fitoterapia

IS - 6

ER -

Pharmacological screening of the methanolic extract of Chenopodium ambrosioides

Abstract

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