Pharmacological screening of the root extract of Securidaca longepedunculata

O. A. Olajide, S. O. Awe, J. M. Makinde

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The methanolic extract of the root of S. longepedunculata was screened for anti-inflammatory, analgesic and anticonvulsant activities, as well as for effects on phenobarbitone sleeping time. The extract produced an inhibition of the carrageenan-induced rat paw oedema, an inhibition of writhings induced by acetic acid, a complete (100%) protection against leptazol-induced convulsion, and a potentiation of the phenobarbitone sleeping time in mice.

Original languageEnglish
Pages (from-to)245-248
Number of pages4
JournalFitoterapia
Volume69
Issue number3
Publication statusPublished - 6 Aug 1998
Externally publishedYes

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