Pharmacological screening of the root extract of Securidaca longepedunculata

O. A. Olajide, S. O. Awe, J. M. Makinde

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

The methanolic extract of the root of S. longepedunculata was screened for anti-inflammatory, analgesic and anticonvulsant activities, as well as for effects on phenobarbitone sleeping time. The extract produced an inhibition of the carrageenan-induced rat paw oedema, an inhibition of writhings induced by acetic acid, a complete (100%) protection against leptazol-induced convulsion, and a potentiation of the phenobarbitone sleeping time in mice.

LanguageEnglish
Pages245-248
Number of pages4
JournalFitoterapia
Volume69
Issue number3
Publication statusPublished - 6 Aug 1998
Externally publishedYes

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Securidaca
Phenobarbital
Pharmacology
Carrageenan
Non-Steroidal Anti-Inflammatory Agents
Acetic Acid
Anticonvulsants
Edema
Seizures

Cite this

Olajide, O. A. ; Awe, S. O. ; Makinde, J. M. / Pharmacological screening of the root extract of Securidaca longepedunculata. In: Fitoterapia. 1998 ; Vol. 69, No. 3. pp. 245-248.
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Pharmacological screening of the root extract of Securidaca longepedunculata. / Olajide, O. A.; Awe, S. O.; Makinde, J. M.

In: Fitoterapia, Vol. 69, No. 3, 06.08.1998, p. 245-248.

Research output: Contribution to journalArticle

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