Pharmacological screening of the root extract of Securidaca longepedunculata

O. A. Olajide; S. O. Awe; J. M. Makinde

Pharmacological screening of the root extract of Securidaca longepedunculata

O. A. Olajide, S. O. Awe, J. M. Makinde

University of Ibadan

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

The methanolic extract of the root of S. longepedunculata was screened for anti-inflammatory, analgesic and anticonvulsant activities, as well as for effects on phenobarbitone sleeping time. The extract produced an inhibition of the carrageenan-induced rat paw oedema, an inhibition of writhings induced by acetic acid, a complete (100%) protection against leptazol-induced convulsion, and a potentiation of the phenobarbitone sleeping time in mice.

Original language	English
Pages (from-to)	245-248
Number of pages	4
Journal	Fitoterapia
Volume	69
Issue number	3
Publication status	Published - 6 Aug 1998
Externally published	Yes

Cite this

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title = "Pharmacological screening of the root extract of Securidaca longepedunculata",

abstract = "The methanolic extract of the root of S. longepedunculata was screened for anti-inflammatory, analgesic and anticonvulsant activities, as well as for effects on phenobarbitone sleeping time. The extract produced an inhibition of the carrageenan-induced rat paw oedema, an inhibition of writhings induced by acetic acid, a complete (100\%) protection against leptazol-induced convulsion, and a potentiation of the phenobarbitone sleeping time in mice.",

keywords = "Analgesic activity, Anti-inflammatory activity, Anticonvulsant activity, Phenobarbitone sleeping time, Securidaca longepedunculata",

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year = "1998",

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T1 - Pharmacological screening of the root extract of Securidaca longepedunculata

AU - Olajide, O. A.

AU - Awe, S. O.

AU - Makinde, J. M.

PY - 1998/8/6

Y1 - 1998/8/6

N2 - The methanolic extract of the root of S. longepedunculata was screened for anti-inflammatory, analgesic and anticonvulsant activities, as well as for effects on phenobarbitone sleeping time. The extract produced an inhibition of the carrageenan-induced rat paw oedema, an inhibition of writhings induced by acetic acid, a complete (100%) protection against leptazol-induced convulsion, and a potentiation of the phenobarbitone sleeping time in mice.

AB - The methanolic extract of the root of S. longepedunculata was screened for anti-inflammatory, analgesic and anticonvulsant activities, as well as for effects on phenobarbitone sleeping time. The extract produced an inhibition of the carrageenan-induced rat paw oedema, an inhibition of writhings induced by acetic acid, a complete (100%) protection against leptazol-induced convulsion, and a potentiation of the phenobarbitone sleeping time in mice.

KW - Analgesic activity

KW - Anti-inflammatory activity

KW - Anticonvulsant activity

KW - Phenobarbitone sleeping time

KW - Securidaca longepedunculata

UR - https://www.scopus.com/pages/publications/0031821302

M3 - Article

AN - SCOPUS:0031821302

SN - 0367-326X

VL - 69

SP - 245

EP - 248

JO - Fitoterapia

JF - Fitoterapia

IS - 3

ER -

Pharmacological screening of the root extract of Securidaca longepedunculata

Abstract

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