Pharmacological studies on the leaf of Psidium guajava

O. A. Olajide, S. O. Awe, J. M. Makinde

Research output: Contribution to journalArticlepeer-review

88 Citations (Scopus)


The methanol extract of the leaves of Psidium guajava was found to inhibit paw oedema induced by carrageenan in rats and pain induced by acetic acid in mice, and exhibited an antipyretic effect. Oral administration of the extract reduced intestinal transit time and prevented castor oil-induced diarrhoea in mice. A CNS depressant activity was exhibited by the extract by potentiating the phenobarbitone sleeping time in mice.

Original languageEnglish
Pages (from-to)25-31
Number of pages7
Issue number1
Publication statusPublished - 1 Feb 1999
Externally publishedYes


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