Pharmacological studies on the leaf of Psidium guajava

O. A. Olajide, S. O. Awe, J. M. Makinde

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

The methanol extract of the leaves of Psidium guajava was found to inhibit paw oedema induced by carrageenan in rats and pain induced by acetic acid in mice, and exhibited an antipyretic effect. Oral administration of the extract reduced intestinal transit time and prevented castor oil-induced diarrhoea in mice. A CNS depressant activity was exhibited by the extract by potentiating the phenobarbitone sleeping time in mice.

Original languageEnglish
Pages (from-to)25-31
Number of pages7
JournalFitoterapia
Volume70
Issue number1
DOIs
Publication statusPublished - 1 Feb 1999
Externally publishedYes

Fingerprint

Psidium
Pharmacology
Central Nervous System Depressants
Castor Oil
Antipyretics
Carrageenan
Phenobarbital
Acetic Acid
Oral Administration
Methanol
Diarrhea
Edema
Pain

Cite this

Olajide, O. A. ; Awe, S. O. ; Makinde, J. M. / Pharmacological studies on the leaf of Psidium guajava. In: Fitoterapia. 1999 ; Vol. 70, No. 1. pp. 25-31.
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Pharmacological studies on the leaf of Psidium guajava. / Olajide, O. A.; Awe, S. O.; Makinde, J. M.

In: Fitoterapia, Vol. 70, No. 1, 01.02.1999, p. 25-31.

Research output: Contribution to journalArticle

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