Photofunctional cyclometallated iridium(iii) polypyridine methylsulfone complexes as sulfhydryl-specific reagents for bioconjugation, bioimaging and photocytotoxic applications

Lili Huang, Peter Kam Keung Leung, Lawrence Cho Cheung Lee, Guang Xi Xu, Yun Wah Lam, Kenneth Kam Wing Lo

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


We report herein near-infrared (NIR)-emitting cyclometallated iridium(iii) complexes bearing a heteroaromatic methylsulfone moiety as sulfhydryl-specific reagents; one of the complexes was conjugated to cysteine and cysteine-containing peptides and proteins for bioimaging and photocytotoxic applications.

Original languageEnglish
Pages (from-to)10162-10165
Number of pages4
JournalChemical Communications
Issue number73
Early online date8 Aug 2022
Publication statusPublished - 18 Sep 2022
Externally publishedYes

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