Poly Lactic Acid Fibre Based Biodegradable Stents and Their Functionalization Techniques

Rita Rebelo, Nívea Vila, Sohel Rana, Raul Fangueiro

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

Commercial stents, especially metallic ones, present several disadvantages, and this gives rise to the necessity of producing stents with different materials, like natural polymers, in order to improve their biocompatibility and minimize the disadvantages of metallic ones. Another way to improve the biocompatibility and create a stent with less thrombogenic and inflammatory materials is through surface functionalization. This possibility allow to provide new functionalities to materials, like drug release or higher biocompatibility. One of the most used technique for stents functionalization is Layer by Layer (LBL). The principle of this technique is based on the alternating adsorption of materials with opposite charge or functional groups, in order to form integrated thin films. This review paper discusses some applications of natural-based polymers in stents, namely polylactic acid (PLA) for stent development and chitosan for biocompatible coatings of stents. Furthermore, some effective stent functionalization techniques will be discussed, namely Layer by Layer technique.
Original languageEnglish
Title of host publicationNatural Fibres: Advances in Science and Technology Towards Industrial Applications
Subtitle of host publicationFrom Science to Market
EditorsRaul Fangueiro, Sohel Rana
PublisherSpringer Netherlands
Pages331-342
Number of pages12
ISBN (Electronic)9789401775151
ISBN (Print)9789401775137
DOIs
Publication statusPublished - 11 Feb 2016
Externally publishedYes

Publication series

NameRILEM Bookseries
PublisherSpringer, Dordrecht
Number1
Volume12
ISSN (Print)2211-0844
ISSN (Electronic)2211-0852

Fingerprint

Stents
Fibers
Biocompatibility
Natural polymers
poly(lactic acid)
Chitosan
Functional groups
Polymers
Adsorption
Thin films
Coatings

Cite this

Rebelo, R., Vila, N., Rana, S., & Fangueiro, R. (2016). Poly Lactic Acid Fibre Based Biodegradable Stents and Their Functionalization Techniques. In R. Fangueiro, & S. Rana (Eds.), Natural Fibres: Advances in Science and Technology Towards Industrial Applications: From Science to Market (pp. 331-342). (RILEM Bookseries; Vol. 12, No. 1). Springer Netherlands. https://doi.org/10.1007/978-94-017-7515-1_25
Rebelo, Rita ; Vila, Nívea ; Rana, Sohel ; Fangueiro, Raul. / Poly Lactic Acid Fibre Based Biodegradable Stents and Their Functionalization Techniques. Natural Fibres: Advances in Science and Technology Towards Industrial Applications: From Science to Market. editor / Raul Fangueiro ; Sohel Rana. Springer Netherlands, 2016. pp. 331-342 (RILEM Bookseries; 1).
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Rebelo, R, Vila, N, Rana, S & Fangueiro, R 2016, Poly Lactic Acid Fibre Based Biodegradable Stents and Their Functionalization Techniques. in R Fangueiro & S Rana (eds), Natural Fibres: Advances in Science and Technology Towards Industrial Applications: From Science to Market. RILEM Bookseries, no. 1, vol. 12, Springer Netherlands, pp. 331-342. https://doi.org/10.1007/978-94-017-7515-1_25

Poly Lactic Acid Fibre Based Biodegradable Stents and Their Functionalization Techniques. / Rebelo, Rita; Vila, Nívea; Rana, Sohel; Fangueiro, Raul.

Natural Fibres: Advances in Science and Technology Towards Industrial Applications: From Science to Market. ed. / Raul Fangueiro; Sohel Rana. Springer Netherlands, 2016. p. 331-342 (RILEM Bookseries; Vol. 12, No. 1).

Research output: Chapter in Book/Report/Conference proceedingChapter

TY - CHAP

T1 - Poly Lactic Acid Fibre Based Biodegradable Stents and Their Functionalization Techniques

AU - Rebelo, Rita

AU - Vila, Nívea

AU - Rana, Sohel

AU - Fangueiro, Raul

PY - 2016/2/11

Y1 - 2016/2/11

N2 - Commercial stents, especially metallic ones, present several disadvantages, and this gives rise to the necessity of producing stents with different materials, like natural polymers, in order to improve their biocompatibility and minimize the disadvantages of metallic ones. Another way to improve the biocompatibility and create a stent with less thrombogenic and inflammatory materials is through surface functionalization. This possibility allow to provide new functionalities to materials, like drug release or higher biocompatibility. One of the most used technique for stents functionalization is Layer by Layer (LBL). The principle of this technique is based on the alternating adsorption of materials with opposite charge or functional groups, in order to form integrated thin films. This review paper discusses some applications of natural-based polymers in stents, namely polylactic acid (PLA) for stent development and chitosan for biocompatible coatings of stents. Furthermore, some effective stent functionalization techniques will be discussed, namely Layer by Layer technique.

AB - Commercial stents, especially metallic ones, present several disadvantages, and this gives rise to the necessity of producing stents with different materials, like natural polymers, in order to improve their biocompatibility and minimize the disadvantages of metallic ones. Another way to improve the biocompatibility and create a stent with less thrombogenic and inflammatory materials is through surface functionalization. This possibility allow to provide new functionalities to materials, like drug release or higher biocompatibility. One of the most used technique for stents functionalization is Layer by Layer (LBL). The principle of this technique is based on the alternating adsorption of materials with opposite charge or functional groups, in order to form integrated thin films. This review paper discusses some applications of natural-based polymers in stents, namely polylactic acid (PLA) for stent development and chitosan for biocompatible coatings of stents. Furthermore, some effective stent functionalization techniques will be discussed, namely Layer by Layer technique.

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KW - Artificial stent

KW - Chitosan

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Rebelo R, Vila N, Rana S, Fangueiro R. Poly Lactic Acid Fibre Based Biodegradable Stents and Their Functionalization Techniques. In Fangueiro R, Rana S, editors, Natural Fibres: Advances in Science and Technology Towards Industrial Applications: From Science to Market. Springer Netherlands. 2016. p. 331-342. (RILEM Bookseries; 1). https://doi.org/10.1007/978-94-017-7515-1_25